IV Pain Meds, Patches, Pumps: How To Take Analgesics?

Last Updated: March 24, 2024

Roger Weiss Authored by Roger Weiss, MD
Dr. Ash Bhatt Reviewed by Dr. Ash Bhatt
0 sources cited

Painkillers are mostly taken orally as pills or capsules. Most oral non-opioids are available over the counter, but a patient can also get the opioidย pain medication online by a doctorโ€™s prescription. The liquid pain meds can be taken by children or adults who cannot swallow pills or capsules. Painkillers may also be taken in different ways such as injections, topical gels, suppositories, dermal patches, nasal sprays, and as a pump.ย Sublingual and nasal pain meds are used only for treating breakthrough pain of cancer. The stronger painkillers are taken in the form of a pump to release the medication over a period of time slowly.

Injections And Infusions

There are some painkillers that can be taken by injection, either intramuscularly (IM) or intravenously (IV). These drugs can also be taken by infusion over a period of time. The pain medication injection list may contain non-opioid OTC painkillers or prescribed opioids. Some patients are advised to take intravenous pain medications, such as acetaminophen and non-steroidal anti-inflammatory drugs for immediately relieving severe pain after an accident. On the other hand, IM pain meds are taken for relieving mild and moderate pain. Some injectable pain meds, such as opioids, are taken intravenously at regular intervals for relieving pain after surgery, as the patient may still be under the influence of anesthesia and cannot take painkiller pills or capsules orally. Also, taking IV painkillers after labor is common, but should be used as prescribed.

The main advantage of taking IV medication is that it gives its effect rapidly after a few minutes of administration.

There are seriousย side effects of pain meds, such as increased heart rate and respiratory depression may affect fetus while taking it intramuscularly after labor. According to a study published in the Journal of International Medical Research, IV pain meds have greater pain relief than IM pain medications without breath depression.

Injections of pain medications

Oral Pain Meds

Theย popular painkillers are available orally in the form of pills and capsules. It is recommended to use liquid pain medications for a patient who cannot swallow the tablets or capsules as in infants and the elderly. The liquid painkillers for adults can be used after oral surgery or oropharyngeal cancer via enteral feeding. Liquid pain medications are completely absorbed in about 15 to 30 minutes after taking it. So, it gives its effect more rapidly than tablets and capsules. The oral pain meds cannot be taken after surgery as the patient cannot take any medication orally and also not taken while the patient is vomiting. Oral pain medication is not completely absorbed into the blood as it is subject to the first-pass metabolism of the liver.

Painkillers Pills And Capsules

The pain medication pills are used for adults to relieve acute and chronic episodes of pain. The painkillers pills list includes acetaminophen, NSAIDs, and opioids. Pills and capsules are not completely absorbed as it is metabolized by the liver before entering the blood. The pain medication pills are absorbed after about 1 to 2 hours after taking it. So, it takes more time to start their effect more than liquid form. Non-steroidal anti-inflammatory drugs such as ibuprofen and ketoprofen pills are effectiveย teeth pain medication. It is not recommended to takeย painkillers during pregnancy except taking acetaminophen pills as it is the safest medication. The pills can be taken after minor surgery for relieving mild and moderate pain. Most painkiller pills cannot be used while there is an inflammation in the stomach as it may increase gastric bleeding.

Painkillers Pills And Capsules

Buccal And Sublingual Pain Medications

Sublingual pain meds are taken under the tongue without swallowing to dissolve and diffuse the medication into the blood, while buccal painkillers are taken between the gums and cheek and also absorbed directly into the blood. One of the major advantages of taking sublingual pain medication is that it is absorbed rapidly and gives its effect faster than oral painkiller pills. Sublingual pain meds are not subject to the hepatic first-pass metabolism, so it is completely absorbed into the blood. The effect is achieved after 15 minutes of taking sublingual painkillers. Therefore, using short-acting sublingual painkillers such as fentanyl sublingual pills is preferred for rapid relief of severe pain. However, using these types may irritate the mouth while taking it with a patient has mouth sores or lesions.

Pain Medication Patches

The pain medication patches are applied onto the skin to release the medication over about 3 to 7 days slowly. It may take 24 hours before the effect appears. This type of painkillers is completely absorbed into the blood over a long period of time. Transdermal pain medications usually contain opioids such as fentanyl and buprenorphine. This type of medication is used for relieving chronic pain.

The patient shouldnโ€™t take alcohol when using patches, as usingย painkillers with alcohol may increase the risk of side effects such as nausea and drowsiness. Mild withdrawal symptoms may appear in the newborn baby whose mother takes painkiller patches during pregnancy.

How to ask doctor for stronger pain meds patches, if the previously prescribed ones no longer work as expected? Before prescribing strong pain patch medication, the doctor should implement aย pain medication contract with patients to ensure that the patient takes the medication correctly.

Pain Pumps

The painkillers may be administered directly to the site of pain using an implanted pump. This pump is inserted under the skin in the abdomen to continuously deliver small quantities of the medication at a constant rate for a long period of time. The pump can be periodically refilled with the medication every 1 to 3 months. It is used to treat chronic pain that cannot be relieved by oral meds or surgery. Moreover, pain pump medication is used when the patient cannot swallow. The pump works more efficiently than oral pills or capsules because it delivers the drug directly into the spinal fluid, and not a subject for the first-pass metabolism of the liver. On the other hand, the pump may cause serious complications such as infection, leakage of spinal fluid, and moving the pump within the body. The painkiller overdose symptoms may occur as a result of these complications.

Topical Pain Relievers

Topical painkillers are applied directly to the skin for temporarily relieving chronic pain. They can be available as creams, gels, and rubs. Most topical forms are available over the counter such as a natural painkillers and some require a doctor’s prescription. The topical pain relievers are suitable for patients who have difficulty swallowing or who cannot tolerate the injectable route. The topical form rarely produces side effects as oral pills and liquids. Topical creams and gels have several advantages over oral pills; it has less systemic side effects, not undergoing first pass-metabolism, and target pain site only with low doses of the drug. However, these forms may increase the risk of skin swelling and irritation.

Suppository Pain Medications

Non-opioids andย prescription painkillers are available in that form. The effect of rectal suppositories is achieved after about 1 hour of administration. The rectal pain medication suppository is absorbed directly into the blood without hepatic metabolism. The suppository pain medications are prescribed for patients who cannot swallow oral liquids and capsules or the one who has severe vomiting and nausea. It is also prescribed for unconscious patients. The frequent use of this form may cause mucosal irritation of rectum and may change the bowel function and movement. Stopping opioids suppositories without the doctor’s advice may experienceย pain medication withdrawal symptoms like nausea, depression, muscle cramping anxiety, and agitation.
rectal pain medication

Nasal Sprays

There are some NSAIDs and opioids that can be taken intranasally. The nasal pain medication is rapidly absorbed through the nasal capillary network and delivered to the blood. It can be used in patients with a history of chronic pain in lower doses. The intranasal route is painless, noninvasive, with a rapid onset of action. It bypasses the first-pass metabolism with higher bioavailability. It has mild side effects with a lower risk of overdose. The nasal spray pain medications may cause local side effects with short term use such as nasal irritation and irreversible damage of nasal cilia. Some intranasal opioids such as fentanyl may cause systemic side effects. However, respiratory depression does not occur with nasal painkillers.

Gas And Air

Gas and air is a colorless, odorless mixture of oxygen and nitrous oxide gas available in hospitals only. It is a mild painkiller used for young people and children during short procedures. It is the common method for relieving labor pain without side effects on the baby. Gas and air do not completely relieve pain, but it can rapidly reduce it. It is used efficiently, and its effects wear off once stop gas breathing. Drowsiness, nausea, and mild headache are the expected side effects of gas painkiller. Dry mouth may occur with the long term use of gas and air painkiller.

How Painkillers Are Abused

Many people use pain medications for non-medical purposes. Except abusing the common pills by extending the prescribed dosage, recreational users smoke and snort opioid pain medications. Ways of taking analgesics listed below are dangerous and may cause lung and mucosal damage, and many other adverse effects, as well as lead to addiction development and overdose.

Smoking Painkillers

Some abusers smoke painkillers to get high, by heating the substance. The effect of opioids starts after about 10 to 15 minutes of inhaling it. This route of taking painkillers has no therapeutic indication. Smoking painkillers can be as dangerous as the injectable route. The chronic use of smoking opioids can cause respiratory depression and chronic coughing.

Snorting Painkillers

There is another route of taking painkillers is by snorting it. The abusers crush the tablet into a powder to snort it. While snorting painkillers, the medication is rapidly absorbed through the nasal membrane and then goes directly into the blood circulation without undergoing hepatic metabolism.

Snorting opioids can cause a sudden decrease in blood pressure, respiratory depression, and cardiac arrest. Some opioids, such as hydrocodone can lead toย hypersensitivity pneumonitis when snorting it.

man is snorting painkillers

Choose The Safe Way Of Taking Pain Medications

There are different ways of taking painkillers. Topical painkillers are the safest way of taking the medication with fewer side effects without the painful sensation of injections. It is also suitable for those who cannot swallow pills or capsules.

Itโ€™s also essential to notify the doctor about any other medications taken, as the dangerous interactions may occur. For example, mixing sleeping pills with painkillers of opioid class may cause an overdose.

Snorting and smoking painkillers are the most dangerous ways of taking medication. In these ways, the drug abusers may take high doses of painkillers, leading to dangerous side effects and may cause addiction. A person who smokes analgesics may experience more intense withdrawal symptoms.

The painkillerย addiction treatment helps in overcoming withdrawal symptoms and avoiding relapse. It is recommended to know whatย rehab centers can accelerate the recovery of addiction.


Page Sources

  1. Jo Noble-Gresty. Recent and Upcoming Approaches in the Management of Cancer Breakthrough Pain. 2010. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590051/
  2. Jing-fen Jin, Ling-ling Zhu, Meng Chen, Hui-min Xu, Hua-fen Wang, Xiu-qin Feng, Xiu-ping Zhu, Quan Zhou. The optimal choice of medication administration route regarding intravenous, intramuscular, and subcutaneous injection. 2015. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494621/
  3. Malaika Babb, Gideon Koren, Adrienne Einarson. Treating pain during pregnancy. 2010. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809170/
  4. Lakshmi Kant Pathak, Vimala Vijayaraghavan. Hydrocodone snorting leading to hypersensitivity pneumonitis. 2016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900771/

Published on: September 25th, 2019

Updated on: March 24th, 2024

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