Midazolam – How is it Used and its Side Effects

Addiction Resource > Addictive Substances: The Anatomy of Drug Addiction > Midazolam – How is it Used and its Side Effects

The Use of Midazolam and Its Side effects

What is Midazolam?

First of all, Midazolam belongs to a class of benzodiazepines. In addition, its component works in the brain, particularly the central nervous system. As a result, the effect will result in sleepiness, relaxed muscles, and lessen the signs of anxiety. Additionally, This drug may also lead to temporary memory loss.

How is Midazolam Used

Presently, they prescribe the drug as anesthesia to sedate patients. It includes those about to undergo medical procedures like surgery. Additionally, doctors also give this drug to treat other conditions like treatment for anxiety under strict supervision. It is because it could cause serious breathing problems. Moreover, when these breathing problems affect a patient, this could lead to brain damage or worst death.

When is Midazolam not Recommended?

Individuals with the following conditions, should not take the drug:

  • Allergic reactions to the drug
  • Patients with acute narrow-angle glaucoma
  • Individuals diagnosed with psychosis
  • Patients with liver disease
  • Anyone showing abnormal vital signs due to alcohol intoxication
  • Patients taking medications such as delavirdine, efavirenz, ritonavir (HIV protease inhibitor) or sodium oxybate (GHB)
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What to do before taking Midazolam?

No doubt, before taking it, you must inform your medical provider about any of the following medical conditions:

  • Women who are pregnant, planning to conceive, or breastfeeding
  • Taking other medication, health or dietary supplements
  • Are prone to allergy with drugs, food, and substances
  • Currently experiencing breathing problems like COPD and Open-angle
  • Diagnosed with heart, liver or kidney problems
  • Have acquired blood disease porphyria
  • Experiencing depression
  • A history of drug or substance abuse or dependence
  • Have just taken alcohol

Which Medicines may Interact With Midazolam

Of course, you must notify the doctor or healthcare professional if you are taking any of these medicines:

  • Carbamazepine, rifampin, St. John’s wort
  • Azole antifungals (itraconazole)
  • Barbiturates (Phenobarbital)
  • Clozapine
  • Delavirdine
  • Diltiazem
  • Disulfiram
  • Efavirenz
  • Grapefruit juice
  • Ritonavir (HIV protease inhibitor)
  • Ketolides (telithromycin)
  • Macrolides (erythromycin)
  • Narcotic pain drugs (codeine)
  • Nefazodone
  • Omeprazole
  • Sodium oxybate (GHB)
  • Valproic acid
  • Verapamil

Furthermore, these medicines may cause adverse side effects leading to low blood pressure, respiratory problems, and intense sedation.

What is the Proper use of Midazolam

MidazolamIf your doctor prescribed Midazolam, you must follow the instruction on doses found on the label strictly. In addition, you should also apply these best practices when under this prescription. Firstly, they usually administer the drug via injection. Above all, it must happen at a medical clinic or hospital. However, if you find Midazolam with particles or form of discoloration, cracked or damaged vial, don’t use it. Discard it properly. In addition, store this medicine including needles or syringe away from children and pets. No doubt, never reuse needles or syringes. You should employ proper disposal after use. In any case, if you miss a dose, call your doctor immediately. Of course, don’t hesitate to ask questions or anything that bothers you about the use of this drug.

Safety Information About Midazolam

Firstly, This medicine could cause drowsiness. Therefore, Individuals taking the drug must not drive and operate machinery. Secondly, never drink alcohol or take other medications that could cause drowsiness like tranquilizers while using the drug. Thirdly, this drug could cause temporary memory loss for several hours. Fourth, if you are near old people and children, you should take Midazolam with caution. They are more prone to experience adverse side effects.

Finally, pregnant and breastfeeding women must not use the drug due to the harmful effect to the fetus.

Incidentally, if you are using Midazolam for an extended period, there is a high percentage of developing high tolerance. As a result, it could lead to dependency and addiction. Furthermore, If you have used this medicine for a long time and at high doses and quit abruptly, the following withdrawal symptoms could be visible:

  • Rapid heartbeat
  • Hallucinations
  • Muscle pain
  • Seizures
  • Stomach cramps
  • Sweating
  • Body tremors
  • Nausea
  • Vomiting

Common Side Effects While Taking Midazolam

Actually, the side effects of the drug could range from minimal to worst. Of course, this depends on a number of doses, a length of use as well as a case of an overdose. Below are the common side effects while under Midazolam prescription:

  • Feeling of restlessness
  • Headache
  • Inability to control oneself
  • Lack of balance
  • Irritability
  • Noisy breathing
  • Not breathing
  • Hallucinations
  • Slurred speech
  • Inability to respond quickly
  • Difficulty in speaking
  • Unconsciousness
  • Lack of muscle coordination
  • Tremors

In fact, if you suspect someone with Midazolam overdose, you must bring them to the hospital for immediate medical assistance. It is due to these dangerous side effects:

  • Loss of consciousness
  • Unexplained drowsiness
  • Difficulty with coordination
  • Change in consciousness

In rare cases, other side effects of Midazolam are:

  • Blurry vision
  • Double vision
  • Hiccups
  • Drooling of mouth
  • Gagging
Midazolam is a class of benzodiazepine drug, commonly prescribed for patients about to undergo surgery to maintain sedation. Prolonged used of Midazolam could lead to serious side effects including one’s dependence and addiction.