Meloxicam Withdrawal: Does One Goes Cold Turkey When Stopping Mobic?

Last Updated: July 17, 2020

Authored by Olivier George, Ph.D.

Meloxicam is a painkiller and an anti-inflammatory agent that helps in relieving chronic pains and conditions such as Rheumatoid Arthritis. This drug is available only with a prescription from a medical doctor. Patients suffering from chronic pain may end up abusing the drug in an attempt to find relief, not knowing that the abuse of the drug can result in severe side effects and fatal health complications, including heart and kidney failure. Mobic takes up to 80 hours to exit one’s system completely, and therefore, it is crucial to identify the signs and symptoms of Meloxicam withdrawal and seek professional help before stopping the intake of medicine. This step helps to prevent any serious health complications in the long run.

Can One Stop Meloxicam Abruptly?

Though Mobic is an NSAID drug that does not have any addictive properties like opioids and cannot make a patient high, stopping meloxicam cold turkey doesn’t happen to a patient. Although, abrupt discontinuation is not advisable since Mobic cause adverse effects on the nervous system of a dependent person who has been abusing this medicine or taking it for prolonged durations.
Stopping meloxicam abruptly may result in some severe side effects and health complications. Thus it is crucial to seek professional treatment before undergoing meloxicam withdrawal.

Adverse Effects From Stopping Meloxicam

Though Meloxicam is known as non-addictive medicine, excessive use or overdose on Mobic can affect a person’s mental and physical well-being. If a dependency is formed or a patient has been taking high amounts of Mobic for prolonged durations sudden discontinuation of an NSAID drug like it can result in the following side effects of stopping Meloxicam: woman feel unwell from mobic holding glass of water

  • Sore throat and flu-like symptoms
  • Allergies (itching and swelling)
  • Breathing Problems
  • Stomach or Back pain
  • Fatigue/Lethargy
  • Increased heart rate
  • Cloudy or bloody urine
  • Digestive issues

Meloxicam withdrawal process can also lead to stomach or bowel problems such as diarrhea, ulcers, and bleeding, as well as liver or kidney damage. Individuals who had been taking Mobic had a high number of liver enzymes in their body. Such health complications can be fatal if left untreated and they may or may not occur with the following warning signs:

  • Stomach pain
  • Bloody vomit
  • Black Stools
  • Heartburn

Contact the medical professional immediately if any such signs or symptoms are present.
Mental dependency on meloxicam medication may also result in the following side effects:

  • Increased agitation
  • Depression
  • Increased pain
  • Restlessness
  • Headaches

Meloxicam Withdrawal Treatment Programs

doctor gives advice about mobic withdrawal to his patientIf Meloxicam withdrawal can’t be made by a patient themselves due to Mobic abuse, for example, this could be an indication that a substance use disorder is developing in an individual and professional help and support is necessary for a successful recovery. Another sign that a professional medical intervention is required is the inability to limit or completely stop the intake of Mobic.
In such cases, the first and the most important step to take is to find a reputed and research-based withdrawal assistance program to control and treat the symptoms of meloxicam abuse. Professional treatment programs enable individuals to find better alternatives to manage their pain that will prevent any future relapse.
Abuse of meloxicam is classified as a mental health disorder that can be treated through a variety of psychological and behavioral therapies along with peer support. If patient experience extreme or uncontrolled pain, a medical professional will suggest the most suitable alternative to alleviate the pain or rehabilitation program, that eases the withdrawal process and treats patient’s conditions.

Meloxicam Withdrawal Warnings

When undergoing a meloxicam withdrawal, patients should avoid the following medications, as they may interact with meloxicam and cause harm:

  • Oral anticoagulants
  • Antiplatelet drugs
  • SSRIs
  • Diuretics
  • Antihypertensives
  • Other NSAIDs
  • Lithium
  • Calcineurin inhibitors
  • Prostaglandin Synthetase Inhibitors

Taking Meloxicam and Lisinopril together, as it may interact with those drugs and result in unpleasant side effects.
Similarly, taking alcohol with Meloxicam is not recommended, as it can increase the chances of stomach bleeding. It should be avoided by patients with a history of asthma, high blood pressure, kidney failure, heart diseases, and hives.
Pregnant or breastfeeding women are not advised to take Mobic as it may harm the unborn fetus or get passed into the mother’s breast milk. They should always consult their doctor before stopping Meloxicam medication.
NSAIDs are known to increase the chances of getting a heart attack, blood clots or stroke. Patients who have recently had a stroke or heart attack should stop taking Meloxicam tablets immediately unless a doctor allows them to continue or prescribes Celebrex instead meloxicam, for example.
Individuals who need help with meloxicam withdrawal should seek immediate help from a health professional who offers research-based drug treatment and recovery programs, as these medications can cause irreversible damage to their health and overall well-being. Appropriate treatment programs such as psychological or behavioral therapies and medical detox programs are available to help patients get rid of their addictions and lead a healthy life.

Page Sources

  1. Goulet JL, Buta E, Brennan M, Heapy A, Fraenkel L., Discontinuing a non-steroidal anti-inflammatory drug (NSAID) in patients with knee osteoarthritis: Design and protocol of a placebo-controlled, noninferiority, randomized withdrawal trial,
  2. McKellar GE, Hampson R, Tierney A, Capell HA, Madhok R., Nonsteroidal antiinflammatory drug withdrawal in patients with stable rheumatoid arthritis,

Published on: May 14th, 2019

Updated on: July 17th, 2020

About Author

Olivier George, Ph.D.

Olivier George is a medical writer and head manager of the rehab center in California. He spends a lot of time in collecting and analyzing the traditional approaches for substance abuse treatment and assessing their efficiency.


Leave a comment

  • Kathy
    I have been taking maloxacam for a few years. I recently ran out and forgot to refill my prescription and I have been experiencing awful diarrhea and upset stomach. Are these side effects of abrupt discontinued use?
  • Jill Weidman
    I stopped taking Meloxicam before a procedure at my doctors request. I had tingling in my skull, legs, arms and even my lips. I was struggling with dizziness and felt absolutely terrible. Once my procedure was over I took my meloxicam and a few hours later the tingling and dizziness was much better. I did not read anything about this affects is this article but that is my experience.
  • Jill Weidman
    I had very similar affects when I stopped Meloxicam for a procedure. I felt absolutely terrible. I hope yours doesn’t last long.
  • Nancy Lowe/Brouwer
    I am hurting so bad in my back and arm right side I know I took too meloxicam this morning. In fact I added 2 ibroprofim too. Then I got scared. Tell me what to do please. Dr said I have arthritis in my lower back but I’m sure I took too many. Pills please reply. H
    • Gene Shue
      It’s never a good idea to seek medical advice from an online site, Please see you doctor.
  • P
    I stopped taking Meloxicam and started having muscle pain in my neck and shoulders. This is the second time this has happened to me. I have not seen this as a side effect? Shortly after starting Meloxicam again the pain subsides.
  • Rebecca Hoon
    OMG! I have COPD, rheumatoid arthritis and fybromyalgia. I was put on this medication 2 years ago, 15 mg a day…. I was just told on September 8th by my dr to stop taking it… I’m now having severe joint pain. Smh. WHY WAS I EVEN PUT ON THIS CRAP!