Meloxicam Side Effects: Does Meloxicam Cause Weight Gain Or Loss?

Last Updated: July 17, 2020

Authored by Olivier George, Ph.D.

Meloxicam or Mobic is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used to treat pain and inflammation associated with arthritis, rheumatoid arthritis, and osteoarthritis. Side effects of meloxicam can range from mild to severe depending on various factors and conditions. Dangers of Mobic cannot be ruled out, so the drug should only be used precisely under prescription given by a medical professional.

Mobic Common Side Effects

Mobic works by blocking the production of enzymes that cause joint inflammation and pain. It is available in tablets and oral suspension. So, what are Mobic adverse effects?
Meloxicam adverse effects include some mild and common ones as well as severe reactions which need immediate attention from a doctor. Some of the common meloxicam side effects are listed below:Young Woman Having Strong Tension Headache

  • Headaches
  • Upset stomach
  • Nausea
  • Diarrhea
  • Bloating
  • Gas in the digestive tract
  • Constipation
  • Dizziness
  • Nervousness
  • Nasal or throat congestion

Some of the other serious side effects of meloxicam tablet are:

  • Bloody stools
  • Chest pain or shortness of breath
  • Fluid retention in the body resulting in swelling
  • Dark vomit
  • Decreased urination
  • Skin rash or bruising

What are the Side Effects of Long Term Use of Meloxicam?

The long-term adverse effects of Mobic include: old man is having a heart attack

  • Liver damage
  • GI perforation
  • Gastrointestinal bleeding
  • Stroke
  • Heart attack

Another long-term adverse reactions of Mobic is the development of stomach ulcers and GI bleeding. Patients who already have a heart condition or high blood pressure are more likely to be affected by meloxicam side effects when used for long durations of time.

Does Meloxicam Cause Weight Loss or Weight Gain?

Woman hands compresses the the fat on the waist Meloxicam side effects do not include weight loss directly. Patients experience nausea and loss of appetite which may contribute towards some weight loss in certain individuals. However, Mobic and weight gain are directly related.

How Does Meloxicam Cause Weight Gain?

Unexpected weight gain while taking Mobic may be caused by the retention of fluid in the body. This results in swelling of the body and increased weight. If weight gain happens, it must be checked by a doctor immediately because meloxicam warnings include unexpected weight gain as a severe adverse reaction of the drug.

Does Meloxicam Raise Blood Pressure?

Doctor Checking Blood Pressure Of A PatientMeloxicam and high blood pressure are associated with each other as another severe adverse reaction of Mobic medicine. When taking meloxicam, high blood pressure can increase the risk of stroke or cardiac arrest. These risks are increased when this 159 pill is used for long durations or taken in high doses. Patients should monitor their intake of meloxicam, and blood pressure should be checked regularly to ensure that it is not raised. In the case of elevated blood pressure, they should consult their doctor without any delay. Mobic and alcohol interactions also can increase blood pressure in patients, so it is recommended to avoid any alcohol intake during Mobic therapy.

Can Meloxicam Cause Allergy?

Some individuals may be experiencing an allergic reaction to meloxicam doses, but that is not a common adverse effect of this drug. Other meloxicam allergy symptoms include skin irritation or skin rash.
However, more severe meloxicam side effects related to allergies include asthma attacks, hives, shortness of breath, and other allergic reactions. Patients who have a history of a similar allergic reaction to aspirin or other NSAIDs should not use Mobic as it will most certainly cause severe adverse effects in those individuals. Such symptoms can also be part of meloxicam side effects.

Mobic Adverse Effects in Pregnancy

What are the dangers of meloxicam in pregnancy? FDA put Mobic in the D pregnancy category. According to studies and trails, this medicine should not be used by pregnant women, especially in the last trimester. Meloxicam should be removed from the system before the last three months of pregnancy. It is believed to cause damage to the fetus. Therefore, it is not advised to be used by breastfeeding women. Meloxicam drug interactions to avoid, especially in pregnancy, include several blood-pressure reducing drugs, aminoglycosides, cyclosporine, and blood-thinning drugs.

Does Meloxicam Thin Blood?

Yes, it does to some extent. When used with other blood thinners, it can cause bleeding which may even be fatal. Mobic interaction with tramadol should also be considered in such situations. There are no specific studies that show whether Mobic is passed on in breast milk or not. Therefore, the drug should be avoided by breastfeeding mothers.

Mobic Adverse Effects in Pediatric Patients

Meloxicam side effects for pediatric patients are the same as that for adults. However, this medicine should only be used to treat rheumatoid arthritis or similar conditions in children who are at least two years old. The safety of this medicine is not established for use in children below the age of 2 years.

What are the Side Effects of Meloxicam When Used in Children over 2 Years Old?

These include nausea, diarrhea, gas in the digestive tract, bloating, skin irritation, and rashes. If the adverse effects persist or worsen with time, patients are advised to contact their doctor immediately.

How to Minimize Meloxicam Adverse Effects?

Doctor and female patient discussing side effects of meloxicamMobic is an NSAID drug that is used to treat pain, swelling, tenderness, and stiffness of joints caused by arthritis and other related conditions. Meloxicam side effects in humans span a wide range of problems that could arise while taking this medicine. Whenever a doctor prescribes the medication, Mobic uses, and side effects are weighed to ensure that the benefits outnumber the adverse reactions.
There are some steps which one might take to minimize the adverse effects of this drug.

These steps include the following:

  • To reduce the less severe gastrointestinal symptoms like heartburn, gas, or bloating, patients should take the medication on a full stomach.
  • Taking this medicine after a meal also reduces the chances of a stomach ulcer or stomach irritation.
  • If Mobic side effects become severe or persist with time, it should be discontinued.
  • Stopping meloxicam might be the option if experiencing severe adverse effects.

Don’t Take Mobic With Other NSAIDs

Can a patient take ibuprofen with meloxicam? Since ibuprofen is also an NSAID, it should not be used with Mobic without consultation from a doctor. Both of them act as a blood thinner. When used together, they increase the chances of internal bleeding and renal toxicity.
Other NSAIDs like Celebrex may be used instead to avoid the severe adverse reactions of Mobic. However, when considering Mobic vs. Celebrex, Celebrex should not be used by patients with heart disease. If adverse effects of Mobic became severe or abuse to this medication has been developed professional addiction treatment is the right step to take.

Page Sources

  1. Richard M Martin, Pipasha Biswas, Ronald D Mann, The incidence of adverse events and risk factors for upper gastrointestinal disorders associated with meloxicam use amongst 19 087 patients in general practice in England: cohort study,
  2. Christopher Eccleston, Emma Fisher, Brian Anderson, Nick MR Wilkinson, Tess E Cooper, Non‐steroidal anti‐inflammatory drugs (NSAIDs) for chronic non‐cancer pain in children and adolescents,
  3. C.S. Mott Children's Hospital, Meloxicam,

Published on: May 14th, 2019

Updated on: July 17th, 2020

About Author

Olivier George, Ph.D.

Olivier George is a medical writer and head manager of the rehab center in California. He spends a lot of time in collecting and analyzing the traditional approaches for substance abuse treatment and assessing their efficiency.


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