Norco consists of Acetaminophen and Hydrocodone. Acetaminophen is a pain relieveris meant for reducing fever, while Hydrocodone is an opioid pain medication which targets the brain for changing how the body responds to pain. The drug is for relieving moderate to severe pain. Norco has analgesic benefits, but its long-term use is not recommended because of its addictive properties.
Half-life of Norco Metabolites
You might face some withdrawal symptoms which are inevitable if you were taking the drug for a long time. According to research, the half-life of hydrocodone is 3.8 hours. On the other hand, the half-life of Acetaminophen is 4 hours. It will take almost 21 hours for hydrocodone and 22 hours for Acetaminophen to leave the body.
When Does Norco Kick in?
The oral form of Norco is available in hydrocodone capsules. Once ingested, the drug dissolves in the stomach and then it is absorbed via GI (Gastrointestinal) tract. After absorption, the effects of the drug start kicking in 30 minutes.
When Does Norco Leave the Body?
Norco will fully leave your system in 20.9 hours. From other sources, we find the half-life of the drug ranges from 3.3 to 4.1 hours, which means that certain individuals will be able to clean the drug out of their system quicker; maybe in 18.15 hours. Some people, however, may take longer than usual; maybe 22.55 hours. The drug can move from your system within just one day, but its metabolite may not leave for up to 2 days.
Factors That Influence How Long Norco Will Stay in the Body
Several factors may affect the rate of Norco and its metabolites’ clearance:
Two people may have taken the same dosage of the drug at the same time and with the same strength, yet there are certain factors which influence the rate of clearance like:
- Age: Older adults often metabolize and excrete drugs at a slow pace because of the slow functioning of liver, kidney and blood flow. Furthermore, they are often on other medications due to common age-related health problems, and this may further delay the drug’s excretion.
- Body Height, Weight, and Fat: A person’s height, weight, and fat are likely to eliminate the drug from the system. If you are a tall person, 5mg of Norco will move out of your system quicker than the individual who has short height and less weight. The smaller dosage you ingest proportionate to the size of your body, the faster Norco will excrete out of your system.
- Genetics: Various genes influence the ability of our bodies to metabolize drugs. By genetics, some individuals have rapid metabolizers, while others are known as poor metabolizers. The rate of metabolism influences the drug’s clearance rate.
If you take Norco with food, it can slow the drug’s absorption, which means it is going to stay in your system longer. If you take it on an empty stomach, the absorption of the drug will speed up.
The urinary pH has a significant impact on the excretion of Norco and its metabolites from the body. The individuals who have acidic urine tends to clear the metabolites more efficiently than the persons who have a highly alkaline urine.
Detection Window for Different Drug Tests
Urine tests, hair tests, saliva tests and blood tests can be performed to detect the metabolites of the drug.
Since the majority of the hydrocodone is eliminated via urine, it is the most efficient way of detecting the consumption of the drug. It is detectable in the urine after 24 hours. However, some of the metabolites may still be detectable up to 2 to 4 days.
To check Norco and its metabolites in hair, usually 20 to 50 follicles of hair are sent to the lab for analysis. For recent ingestion, it ‘s hard to detect hydrocodone in hair because the human body first has to ingest the drug, circulate it throughout the body and show up in the hair only after the growth of new hair.
Norco can be detected for up to 90 days after ingestion. Some of metabolites of the drug present in hair are directly correlated to the amount of the drug ingested. As hair tests are expensive, they are seldom performed.
A considerable amount of saliva needs to be analyzed to perform Saliva test. These tests are not administered because hydrocodone and other metabolites are difficult to detect in oral fluids. However, Norco may remain detectable for four days after ingestion.
Blood tests are not usually preferred for detecting the presence of Norco or its metabolites in the body because they have the shortest detection window. The contents of the drug can be detected in the blood between 1.3 and 24 hours of ingestion.
How Long Does Norco Stay in Your System? – Conclusion
Other than the individual factors, the dosage will also influence the period for which Norco stays in the system. For example, if you have ingested 500 mg of Norco, it will roughly leave your body in 2 weeks. On the other hand, if you have ingested 750 mg of Norco, it may be taken more than three weeks to leave your body.
The longer you have been taking the drug, the longer it will take to leave your system. So, if you have a urine test coming up, chances are the remains of the drug may still be present. The nature of the body will influence how quick the excretion happens. The drug may disappear from your system in 3 to 4 days, but remember, some of its presence may still be detected in the urine test.