Imodium Interaction With Alcohol And Other Medications

Last Updated: June 16, 2020

Authored by Olivier George, Ph.D.

Loperamide interactions with other drugs and substances may change the way this medication works and result in unpredictable consequences. Sometimes, Imodium interactions can be beneficial and improve the patient’s condition. In many cases, however, combining loperamide and other medications may worsen the existing Imodium A-D side effects and pose significant health risks.

Imodium And Alcohol

Risks of Mixing Both

Drinking alcoholic beverages is generally inadvisable during loperamide treatment. Even when the consumption is moderate, Imodium interaction with alcohol can result in heightened side effects of loperamide. It can also make the action of the medicine weaker. In addition, considering what Imodium is used for, mixing Imodium and alcohol can work to counter the drug by worsening existing diarrhea.

Side Effects Of Taking Loperamide And Alcohol

imodium and alcoholThe combination of loperamide and alcohol can aggravate the nervous system side effects of the medication, namely dizziness, sleepiness, difficulty concentrating, and fatigue. Moreover, certain severe symptoms might develop. Those include confusion, impaired thinking, and delusions. Drowsiness is a relatively common side effect of Imodium, and it might linger even after the alcohol is out of the person’s system.

Taking A Large Amount Of Alcohol With Imodium

The worst-case scenario can occur when a person mixes large amounts of alcohol and Imodium.

Imodium Interactions With Other Medications

Many people take other over-the-counter or prescription medicines along loperamide. Certain drugs may be taken to imitate the effects of Imodium Multi-Symptom Relief caplets or boost the effectiveness of the medication. While many loperamide interactions can be beneficial, some can pose a serious threat to a person’s health. It is essential to learn about the most frequent Imodium interactions with other substances and consult with a doctor before changing the dose or introducing new medicines.

Imodium And Metformin

Metformin is a diabetes medication that is known to cause moderate and severe diarrhea in many patients. Individuals can take Imodium with metformin to ease this symptom. Loperamide does not interact with metformin. However, it should be used with caution if any side effects are present since they can worsen the negative symptoms of metformin as well.

Imodium And Omeprazole

imodium drug interactionThose who abuse Imodium sometimes uses the combination of loperamide and omeprazole. Imodium A-D high is hard to achieve since the drug can’t effectively cross the blood-brain barrier by itself. Mixing omeprazole with loperamide allows the latter to display its opioid properties stronger and enables the user to take lower doses of the drug to get the same results. However, it also makes the person more susceptible to the effects of other substances that are present in their system when they take omeprazole.

Imodium And Suboxone

Suboxone is a medication used in opioid replacement therapy that can cause diarrhea. Loperamide and Suboxone can be taken together to ease gastrointestinal side effects of Suboxone as long as the person takes both medicines properly. Large doses of loperamide can induce high and consequently negate Suboxone treatment.

Imodium And Blood Thinners

Some antidiarrheal medicines such as Pepto-Bismol are known to interact with various blood thinners. There are reports of worsened side effects during the concurrent use of loperamide and blood thinners; still, there is little evidence of significant interaction between the medications.

Imodium And Zantac

Imodium drug interaction with Zantac is strong and can be fatal. Ranitidine tends to increase the level of loperamide in blood. This can result in cardiac arrest, irregular heartbeat, and other heart problems. Patients with congenital long QT syndrome, electrolyte disturbances, and conduction abnormalities should be particularly cautious when taking Zantac with loperamide. In some cases, doctors will prescribe Imodium alternative medicines that will not interact with Zantac.

Imodium And Antibiotics

The question of whether a person can take Imodium with antibiotics periodically arises since diarrhea is a side effect of many antibiotic medications. It is generally stated that an individual should not take Imodium with antibiotics because it can interfere with the course of treatment. Antidiarrheals inhibit the intestine’s ability to eliminate toxins, which can lead to various complications. The adverse effects of antibiotics should normally disappear on their own after several days.

Safe Use Of Loperamide With Other Drugs

can i take imodium with antibiotics safelySpecific Imodium drug interactions can lead to serious health conditions and even death. The most hazardous medicines include Zantac, cholestyramine, opioid pain medications, ritonavir, and medicines that affect the heart rhythm.

An individual should avoid using loperamide to treat diarrhea associated with antibiotic treatment. When it comes to other drugs, it is crucial to research potential interactions before taking medicines alongside loperamide. If a person experiences persistent side effects during short-term treatment for mild diarrhea, it is advisable to receive medical consultation. A doctor can prescribe an alternative to any of the conflicting drugs and help avoid long-lasting and dangerous symptoms. If a patient misuses the medication, it is vital to reach drug rehabilitation facilities as soon as possible to get the proper treatment.

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Published on: May 6th, 2019

Updated on: June 16th, 2020

About Author

Olivier George, Ph.D.

Olivier George is a medical writer and head manager of the rehab center in California. He spends a lot of time in collecting and analyzing the traditional approaches for substance abuse treatment and assessing their efficiency.


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