It is crucial to keep yourself and your loved ones safe during the COVID-19 outbreak. Yet addiction may pose even a higher danger than the virus.

Learn about recovery during the pandemic:

Can One Overdose on Adderall? Symptoms and Causes of OD

overdose on adderall

Important InformationThis information is for educational purposes only. We never invite or suggest the use, production or purchase of any these substances. Addiction Resource and it’s employees, officers, managers, agents, authors, editors, producers, and contributors shall have no direct or indirect liability, obligation, or responsibility to any person or entity for any loss, damage, or adverse consequences alleged to have happened as a consequence of material on this website. See full text of disclaimer.

Adderall overdose is not rare and its symptoms are typically identifiable in users. The effects may range from mild symptoms such as restlessness and blurred vision, to loss of consciousness and death in severe cases.

Help Line Woman

Hope Without Commitment

Find the best treatment options.
Call our free and confidential helpline

Most private insurances accepted

Marketing fee may apply

Table of Contents

Can One Overdose on Adderall?

Adderall is a stimulant drug containing amphetamine and dextroamphetamine. It is used for treating narcolepsy, attention deficit hyperactivity disorder (ADHD), and also as a performance enhancer for athletics. But can one OD on Adderall? It is possible and it occurs most commonly in young adults who desire the mental stimulation, physical vigour, and euphoric highs associated its use. However, taking too much adderall may cause serious symptoms.
It reaches its peak levels 3 hours after ingesting the drug. Adderall half-life is 9 to 14 hours, and iit takes about 18 to 28 hours before a dose leaves the body. However, it is available in two forms: Adderall IR vs XR. It’s immediate release form lasts only for 3 hours while the extended release form lasts for 12 hours.
Factors which influence how long the drug stays in the system influence the risk of developing toxic symptoms and how much Adderall to overdose. Some of these factors include:

  • Dosage – The larger the dose of consumed, the longer it stays in the body, and the higher the risk of developing symptoms of Adderall overdose. One may ask how much Adderall is too much. The usual dose of Adderall pills for adults is 5mg to 60 mg daily in divided doses. The dose may be started at 20mg per day. Doses for adolescents starts at 10mg daily daily and is gradually increased by the doctor depending on the individual’s clinical response. Amounts greater than this may cause serious complications. This means abusers are more likely to overdose Adderall because of the large doses they consume.
  • Body Form – People who are overweight or with large body sizes usually eliminate it much faster than people with small body sizes.
  • Drug Interactions – Co-administration with certain drugs such as monoamine oxidase inhibitors including Selegiline, increases the duration of stay of the drug in the system, increasing the risk of overdosing on Adderall. A combination of Adderall and coffee is also not recommended because both coffee contains caffeine which is a stimulant, which may exacerbate the stimulant effects of amphetamine.
  • Genetics – Some individuals are fast metabolizers while others are slow metabolizers. Fast metabolizers have the CYP2D6 coenzyme variant. Individuals with this variant eliminate the drug faster, reducing their risk of developing toxic effects. Drugs that inhibit the CYP2D6 coenzyme, such as Bupropion, Paroxetine, and Fluoxetine increases the duration of stay of the drug in the system and, in turn, the risk of developing toxic effects. So for people who may wonder how much Adderall does it take to od may need to check their gene profile.
  • Frequency of Use – The more frequently an individual uses it, the greater the potential of developing Adderall overdose symptoms. The form of the drug (XR or IR) being used also determines how much Adderall to od. The relatively low value of Adderall and its availability creates the friendly environment for the frequent use.

How Many People Suffer from Adderall Overdose?

The 2016 National Study on Drug Use and Health revealed that 28.6 million overdosed woman lying on the floow unconscious with pills around herAmericans aged 12 and more had used illicit drugs the month before the study. Furthermore, more than 54 million Americans use prescription drugs for non-medical purposes, and the most abused drugs included painkillers, tranquilizers, stimulants, and sedatives. The study reported that more than 1.7 million Americans use stimulants for non-medical purposes; however, doctors still prescribe Adderall as it is one of the most efficient ADHD treatment medicine.
2013 report published on NCBI shows that the number of people who developed Adderall od from non-medical use has increased significantly between 2006 and 2011. Complications from excess non-medical use of amphetamines requiring emergency care visits increased by 156 percent, with friends and family identified as the main source of the drug, according to the research by Lisa L. Weyandt. Young adults between the ages of 18 and 25 constitute the main population who use amphetamines for non-medical use.
Symptoms of excess use may occur through any of the routes of administration, including intravenous, oral, and nasal. Another common way users achieve the euphoria is to plug Adderall.

What are the Symptoms of Adderall Overdose?

The effects of amphetamines reflect the overstimulation of the brain and this is the key difference it has from narcotics.
Feeling exhausted and tired on Adderall is one of the side effects of the drug and not necessarily a symptom of too much amphetamine. Symptoms of taking too much Adderall may be mild or severe, depending on those factors which influence the Adderall overdose amount.
Mild symptoms include:

  • Headaches
  • Confusion
  • Hyperactivity
  • Vomiting
  • Rapid respiration.

Severe symptoms include:

  • Hallucinations
  • Anxiety
  • Hypertension
  • Tremors
  • Elevated body temperature
  • Death

One may have wondered, can one die from Adderall? Yes, having too much of amphetamine in the system can cause death after consumption of a certain amount. The lethal dose of Adderall is 20 to 25 mg per kilogram of body weight. This means for someone who weighs 60 kg, the dose which can lead to death is 1200mg. Adderall overdose death usually occurs in individuals who use it for non-medical or recreational purposes.

Adderall should be taken only as prescribed. Self-medication and recreational use of the drug is considered as abuse and is illegal.

What are the Complications of Adderall Overdose?

Common complications of excessive consumption of amphetamine include seizures, coma, and death. Serotonin syndrome, characterized by nausea, vomiting, diarrhea, irregular heartbeat, coma, and death, results from co-administration with certain antidepressants.

What to Do in Case of Adderall Overdose?

Once overdose symptoms are suspected, take the following steps:woman overdosed pills, her husband calling to emergency

  • Contact emergency care center. In the United States, call the National Poison Center or 911 emergency phone number and follow their instructions.
  • If the symptoms become worse with rapid pulse and breathing rate, contact a local emergency care department.
  • Stay calm while waiting for emergency care.
  • At the emergency care department, the doctors may pump the drug out of stomach if ingested.
  • A sedative is administered if one is agitated.
  • Intravenous fluids will be administered to restore lost nutrients.

Detoxification involves gradual elimination of amphetamines from the system and managing the ensuing withdrawal symptoms. It is beyond how to come down from Adderall to sleep, to removing all of its stimulant effects from the system. Treatment is essential to prevent relapse and severe complications of addiction. In addition, for individuals taking it for medical purposes, clinicians may advise them on Adderall alternatives with a good safety margin.

How Can One Prevent Adderall Overdose?

To prevent overdose, it should be taken under supervision and not more than the prescribed dose. In addition, do not increase or reduce dosage without a doctor’s approval. Patients should also not use it for recreational purposes without a doctor’s consult, so one will better understand the risk of having harmful amounts of the drug in the body.
Other ways one can prevent overdose is by preventing tolerance. This can be achieved by co-administering magnesium and Adderall, as well as other medications and supplements such as zinc, choline, and glutathione.
Can one overdose on Adderall? Yes, one can, and this is a common occurrence among recreational users of the drug. It presents with many symptoms, including death in severe cases. Taking Amphetamine prescription for medical use alone and at doses prescribed by one’s physician are ways one can prevent overdose.
Being addicted to the drug, one may be referred to an Adderall addiction treatment center for further treatment. One will be managed with a combination of therapies for addicts including psychotherapy and detoxification.

Help Line Woman

Hope Without Commitment

Find the best treatment options.
Call our free and confidential helpline

Most private insurances accepted

Marketing fee may apply

Medically Reviewed By Michael Espelin APRN
Isaak Stotts

About Author

Isaak Stotts, LP

Isaak Stotts is an in-house medical writer in AddictionResource. Isaak learned addiction psychology at Aspen University and got a Master's Degree in Arts in Psychology and Addiction Counseling. After graduation, he became a substance abuse counselor, providing individual, group, and family counseling for those who strive to achieve and maintain sobriety and recovery goals.


Leave a comment