What Are Common And Severe Side Effects Of Robaxin?

Last Updated: January 29, 2020

Robaxin is a muscle relaxant that is used to treat skeletal issues and pain associated with injury, arthritis, and other bone and muscle conditions. Methocarbamol side effects are not severe, in some cases, and they can disappear quickly. However, some people might experience some Robaxin side effects, which should be examined by a doctor, especially if it is a sign of an allergy to methocarbamol. Read along further to find out the common and severe side effects of methocarbamol, check methocarbamol warnings during pregnancy and breastfeeding, and how it can be used safely.

Factors To Consider Before Using Robaxin

Robaxin (methocarbamol) may be prescribed by a doctor if methocarbamol benefits outweigh methocarbamol 500 mg side effects. Nonetheless, some factors are considered before deciding whether or not the use of Robaxin is necessary or not. These factors are described below:


The safety and efficacy of methocarbamol for children below the age of 16 have not been established. There are not enough studies that can determine the effect of Robaxin on children, thereby making it a decision of the doctor to determine if its administration to children will outweigh the presumptive side effects.
Similarly, there are not enough studies to show whether the use of Robaxin in elderly patients will be affected because of their old age. However, the elderly are more likely to experience severe side effects of Robaxin 500mg and 750 mg.

Many multi-colored pills in a Senior's hands


Drug Interactions

Robaxin interactions with other drugs should also be considered before starting its use. Some of these drug interactions might even be fatal. According to the study about the interaction of methocarbamol with ethanol, it was presented that this interaction can lead to combined central nervous system depression and eventually death.
A doctor needs to know all the medications that a patient is using to determine if they can be used with Robaxin. Doctor may adjust the Robaxin dosage to avoid its interactions with the other drugs.

Diseases And Some Health Conditions

Some diseases may aggravate methocarbamol 500 mg side effects, or the diseases may get aggravated because of methocarbamol. A kidney or liver disease might increase methocarbamol side effects because of its slower expulsion from the body. Some diseases like myasthenia gravis may worsen because of Robaxin.

woman experiences nausea and vomiting

Common Side Effects Of Robaxin

Robaxin drug class is a muscle relaxant, and it works by acting on the central nervous system. Thus, it causes some of the common side effects as experienced with the use of other muscle relaxants. Some of the common and less serious Robaxin 500mg and Robaxin 750 mg side effects are listed below:

  • Dizziness
  • Drowsiness
  • Confusion
  • Constipation
  • Flushed feeling
  • Headaches
  • Nausea
  • Vomiting
  • Upset stomach
  • Indigestion
  • Heartburn
  • Stuffy nose
  • Skin rashes
  • Memory problems
  • Blurred vision
  • Loss of balance or coordination
  • Insomnia
  • Uncontrolled eye movements
  • Spinning sensation

Severe Side Effects Of Robaxin

Apart from the common unpleasant effects, some patients might experience severe methocarbamol 750 side effects. These effects could require the urgent attention of a medical professional. Get emergency help if any or more of the following severe side effects occur:

  • Chest pain or discomfort
  • Fever or chills
  • Black or clay-colored stool
  • Dark urine
  • Slower or faster than normal heart rate
  • Difficulty in swallowing
  • Hives especially swelling on the face, eyes, lips, and tongue
  • Numbness of face, hands, and/or feet
  • Seizures
  • Loss of appetite
  • Loss of bladder control
  • Stomach pain
  • Ulcers in the mouth
  • Yellow skin and eyes indicating jaundice
  • Unusual bleeding or bruising
  • Bloody or black vomit
  • Memory problems
  • Joint or muscle pain

Methocarbamol Warnings In Pregnancy And Breastfeeding

Robaxin is a pregnancy Category C medicine, which means that there are not enough studies about the effects and side effects of methocarbamol in pregnant women. It is not known whether methocarbamol will harm an unborn baby. Thus its use is usually avoided in pregnancy unless considered by the doctor to be necessary. The effects of Robaxin and breastfeeding have also not been established, and there is not enough research in this regard.
Young pregnant woman visiting doctor
According to this publication about the drug details of methocarbamol, it is stated that methocarbamol is excreted in the milk of dogs. However, there is not enough research to show whether this is the case in humans also. Thus, caution should be exercised when using methocarbamol during breastfeeding.

Signs Of Allergic Reaction To Methocarbamol

The most severe form of an allergic reaction to Robaxin is anaphylaxis. It is a sudden onset of symptoms that can even be fatal. Symptoms of anaphylaxis include:

  • skin rash
  • swelling of the mouth, lips, and tongue
  • lightheadedness
  • shortness of breath
  • chest tightness
  • low blood pressure

Some other symptoms of an allergic reaction to Robaxin are listed below:

  • Hives
  • Difficulty breathing
  • Swelling on the face
  • Swelling of the mouth and tongue.

Safe Use Of Robaxin

Robaxin, like all muscle relaxants, tends to have some common and severe side effects. However, in cases of pain associated with injury and skeletal issues, its use and benefits outweigh its side effects. It is considered a better choice as compared to some other muscle relaxants. For example, considering methocarbamol vs Flexeril, Flexeril cannot be taken for more than 2 to 3 weeks. If Flexeril is stopped abruptly, it can cause withdrawal symptoms in the patient. Methocarbamol has much less number of withdrawal symptoms.
 doctor explaining patient symptoms
To minimize the risks and side effects of methocarbamol, and to ensure the safe use of methocarbamol, there are certain cautions which one can exercise. These are discussed below:

  • Patients should take Robaxin on an empty or full stomach, as prescribed by the doctor.
  • Patients should not exceed the dosage prescribed by the doctor.
  • Patients should not use Robaxin for a longer period than as prescribed by the doctor.
  • Patients should discuss all the drugs they are taking as well as their other medical conditions or diseases with the doctor before he prescribes Robaxin.
  • Patients should not consume alcohol with methocarbamol. Alcohol and some drugs can interact with the drug and cause unpleasant side effects.

Also, patients should remember that Robaxin abuse can happen, and this condition should be treated as fast as possible because of its dangerous consequences. Rehabilitation centers can offer a broad range of services to overcome this addiction effectively.

Page Sources

  1. Ferslew KE, Hagardorn AK, McCormick WF, A fatal interaction of methocarbamol and ethanol in an accidental poisoning, https://www.ncbi.nlm.nih.gov/pubmed/2329339
  2. National Center for Biotechnology Information. PubChem Database, Methocarbamol, https://pubchem.ncbi.nlm.nih.gov/compound/Methocarbamol

Published on: January 29th, 2020

Updated on: January 29th, 2020


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