Buspar And Pregnancy: The Safety Of Use

Last Updated: July 10, 2020

Authored by Isaak Stotts, LP

Pregnancy is a very special period in women’s lives, which commonly may be followed by increased anxiety levels, so a lot of women are curious if it is safe to take Buspirone during pregnancy. Generally, concerns are focused on the effects of Buspar during pregnancy, particularly regarding safety for fetal development. Can Buspar and pregnancy risks be connected? Is taking Buspar while breastfeeding safe for the baby? Follow the article to receive the answers to popular questions regarding the safety of Vanspar during pregnancy.

Learn More About The Safety Of Buspirone During Pregnancy:

Buspar During Pregnancy

Buspar (trade name of Buspirone medicine) is considered as one of the relatively safe anxiolytic drugs, with a comparatively small list of contraindications. It’s commonly prescribed for controlling anxiety, but in some cases, it can be unsafe. It’s especially true about taking Buspar during pregnancy. Various studies state that women who have shown significant symptoms of anxiety during pregnancy are under the risk of complications, including pre-eclampsia, preterm labor, and low birth weight infants. Careful medical monitoring during pregnancy is crucial for women with a previous history of anxiety disorders, it may help to control anxiety symptoms more efficiently.

When comparing this drug with others used for anxiety management it is vital to assess the risk for the future baby. When comparing Lexapro and Buspar as possible treatment options, for example, one must remember that both medications were not extensively studied on this subject matter.
Pregnant Woman In A Drug Store

Pregnancy Category

According to the FDA, the pregnancy category of Buspar is B, so that means that no fetal harm or fertility impairment has been observed during reproductional studies. However, these studies had been performed in rats and rabbits. During the study, rats and rabbits had been receiving doses of Buspirone during pregnancy that were 30 times higher than standard prescribed ones. In humans, there has not been performed an adequate, reliable, and well-controlled study yet. And while animal reproductive studies can’t always predict the influence on the human reproduction process, the Federal Drug Agency recommends using this drug during pregnancy only in case of clear need. Also, how long does it take for Buspar to work? It usually takes up to 60 minutes before the drug kicks in.

Side Effects During Pregnancy

Adverse effects of Buspar on labor and delivery have not been noted in rats, however, the possibility of its presence in the human body is still unknown. So, is Buspirone safe during pregnancy? There is no clear answer to this question because of the lack of research data. So, what are the side effects of Buspar?  There are certain common adverse reactions like drowsiness or euphoria, yet all of them are a subject of investigation because the Buspirone mechanism of action is not researched completely yet.
Doctor Consults Pregnant Woman

Buspar And Breastfeeding

During the first months of life, a child receives most of the nutrients from breast milk. At the same time, harmful substances also can get to the growing organism through it, the same is also true for medications. So, can breastfeeding while on Buspirone have an impact on the infant?

The National Center for biotechnology information states that maternal doses of Buspirone up to 45 mg daily can produce low levels in milk, but the information about the levels and their impact is limited.

Data about long term Buspirone use while breastfeeding or using smaller doses, like Buspar 10mg, is also unavailable. Based on this, it is recommended that patients and doctors consider using another drug, especially while breastfeeding newborns, an infant with low birth weight or prematurely born child. In a patient, who has been taking Buspar during the pregnancy and postpartum, Buspar was detectable in breast milk up to the thirteenth day postpartum. In the serum of a newborn, which was breastfed by mother taking Buspar 45mg daily, Buspirone was detectable up to the thirteenth and twenty-first day postpartum.
Mother Holds A Newborn

Impact On Newborn

It’s hard to predict what impact can be made on a newborn by Buspar use while breastfeeding, there is little to none reliable data about the adverse effects of the medication on people, younger than 18 years. Buspirone can be transferred through breast milk, so it’s also impossible to tell what it will do in an infant body, and how it will be working. And absolutely unpredictable results may be caused by substance abuse, intentional or accidental overdose, and mixing Buspar with other substances, like taking Buspirone and weed.

The Safety Of Mother And Child

While Buspirone is considered to be relatively not harmful to the adult patient, a lot of its aspects are still unknown. There are researches committed, but only in rats and rabbits, yet those are irrelevant for the human reproductive process. Buspar can be transmitted through breast milk but what risks it can pose to the infant are yet to be researched. While anxiety is a common satellite of pregnancy, childbirth, and nursing of the child, it’s important to consult with a healthcare professional about the appropriate choice of anxiolytic, which will not impose a risk upon the health of the mother and child.

In case one becomes addicted to the Vanspar then it is time to seek professional help. Specialists at the outpatient and inpatient drug rehabs will provide all the necessary treatment needed to get out of the addiction loop. A patient will be offered a set of different treatment programs and will be also offered a range of specialized aftercare programs for the former addicts.

Page Sources

  1. Dunkel Schetter, C., & Tanner, L. (2012). Anxiety, depression and stress in pregnancy: implications for mothers, children, research, and practice. Current opinion in psychiatry, 25(2), 141–148. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447112/
  2. FDA, Buspar Drug Facts. https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/18731s39s45lbl.pdf
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Buspirone. [Updated 2018 Oct 31]. https://www.ncbi.nlm.nih.gov/books/NBK501449/

Published on: July 10th, 2020

Updated on: July 10th, 2020

About Author

Isaak Stotts, LP

Isaak Stotts is an in-house medical writer in AddictionResource. Isaak learned addiction psychology at Aspen University and got a Master's Degree in Arts in Psychology and Addiction Counseling. After graduation, he became a substance abuse counselor, providing individual, group, and family counseling for those who strive to achieve and maintain sobriety and recovery goals.


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