Heroin Effects: What It Does to the Brain and Body?

Last Updated: January 6, 2025

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The main effects of heroin are euphoria, sedation, nausea and vomiting, organ damage, collapsed veins, HIV, and psychosis. Heroin is a prohibited opioid derived from morphine that impacts the brain and physical health, causing addiction and cognitive impairments.

Heroin binds opioid receptors in the brain and triggers intense euphoria and pain relief. The short-term effects of heroin use include dry mouth, drowsiness, and slowed breathing. The long-term effects are collapsed veins, liver damage, and severe mental health issues.

Heroin withdrawal is a challenging condition that involves symptoms like restlessness, nausea, and intense cravings. 1.1 million people, or 0.4% of the U.S. population, use heroin each year. 1 million people aged 12 or older may have a heroin use disorder and 10,000 people die each year from an overdose that involves heroin, according to the research titled “Heroin” published by WebMD.

What are the Short-term Effects of Heroin?

The short-term effects of heroin are euphoria, sedation, pain relief, respiratory depression, nausea and vomiting, clouded mental functioning, and drowsiness (nodding off). Below are the details of the short-term effects of heroin.

  • Euphoria: Euphoria is a brief and intense feeling of pleasure that occurs because heroin stimulates opioid receptors in the brain, triggering a surge of dopamine, according to the research titled “Drugs, Brains, and Behavior The Science of Addiction” published by the National Institute on Drug Abuse. This “rush” initiates the cycle of addiction.
  • Sedation: Heroin depresses the central nervous system, causing feelings of relaxation and lethargy, making it difficult to stay alert or perform tasks. This short-term effect of heroin is both psychological and physical.
  • Pain Relief: Heroin temporarily blocks pain signals by interacting with opioid receptors and offers a strong analgesic effect but masking injuries or illnesses, according to the research titled “Drugs, Brains, and Behavior: The Science of Addiction” published by the National Institute on Drug Abuse. Euphoria is a short-term and physical effect of heroin.
  • Respiratory Depression: Respiratory depression refers to slow breathing as heroin suppresses brain activity, which can quickly become life-threatening in cases of overdose.
  • Nausea and Vomiting: Activation of the brain’s chemoreceptor trigger zone leads to stomach upset, nausea, and vomiting, especially in first-time heroin users.
  • Clouded Mental Functioning: Clouded mental functioning refers to impaired cognitive abilities in heroin-addicted individuals. Clouded mental functioning leads to slowed thinking, poor decision-making, and confusion.
  • Drowsiness and “Nodding Off”: Heroin-addicted users frequently drift between wakefulness and sleep and lose awareness of their surroundings. Drowsiness increases the risk of accidents.

What are the Long-term Effects of Heroin?

The long-term effects of heroin are organ damage, respiratory damage, collapsed veins and abscesses, skin infections, HIV, Hepatitis B, cognitive impairment, psychosis, social Isolation, and increased risk of criminal activity. Below are the details of the long-term heroin addiction effects.

  • Organ Damage: Organ damage is a physical symptom as chronic heroin use damages major organs like the liver, kidneys, and heart due to reduced oxygen supply, toxicity, and impurities in the drug.
  • Respiratory Damage: Repeated episodes of respiratory depression weaken lung function and increase the risk of chronic respiratory conditions, pneumonia, and other lung diseases, according to the research titled “Drugs, Brains, and Behavior: The Science of Addiction” published by the National Institute on Drug Abuse.
  • Collapsed Veins and Abscesses: Collapsed veins and abscesses occur after frequent heroin injections damage blood vessels due to unclean practices. This long-term effect of heroin addiction is physical.
  • Skin Infections: Heroin-addicted individuals suffer from conditions like cellulitis or severe bacterial infections, including necrotizing fasciitis, due to poor hygiene.
  • HIV: Sharing contaminated needles significantly increases the risk of HIV transmission to people abusing heroin, a life-threatening infection with severe health implications.
  • Hepatitis B and C: Hepatitis B and C occur after damage to the liver. Unsafe injection practices expose users to hepatitis viruses, leading to chronic liver disease and other complications.
  • Cognitive Impairment: Long-term heroin use disrupts brain function, causing memory loss, attention deficits, and impaired decision-making abilities.
  • Psychosis: Heroin’s prolonged use leads to mental health conditions such as paranoia, hallucinations, and delusions, especially if heroin is mixed with other substances.
  • Social Isolation: Social isolation is a behavioral effect of heroin use. The compulsive nature of heroin use leads to the neglect of relationships, work, and responsibilities, isolating the individual from their social support system.
  • Increased Risk of Criminal Activity: The financial strain of addiction drives users toward illegal activities such as theft or drug trafficking to support their habit.

What are the Effects of Heroin Withdrawal?

The effects of heroin withdrawal are muscle and bone pain, insomnia, cold flashes, uncontrollable leg movements, intense cravings, and suicidal thoughts.

Heroin Withdrawal refers to the physical and psychological symptoms that occur when someone dependent on heroin stops using the drug. Withdrawal happens because the body has become reliant on heroin’s effects, especially its impact on dopamine production, and struggles to function without it. Symptoms begin within hours and may last for days or weeks.

The effects of heroin withdrawal are listed below.

  • Muscle and Bone Pain: Muscle and bone pain is one of the main symptoms of heroin withdrawal in which individuals feel intense pain in muscles and bones, deep and aching. Muscle and bone pain occurs because heroin numbs pain and when it’s absent, the body reacts by amplifying discomfort. The pain is often severe and affects joints, muscles, and bones, making it difficult to move or perform basic tasks.
  • Insomnia: Heroin withdrawal leads to significant sleep disturbances, including an inability to fall or stay asleep (insomnia). The heroin withdrawal process increases anxiety and restlessness, further intensifying the difficulty of sleeping. Insomnia has both a physical and psychological effect as it involves the body’s inability to relax, as well as heightened emotional distress.
  • Cold Flashes: Cold flashes, accompanied by chills or sweating are common during heroin withdrawal. These episodes are the body’s response to heroin’s absence, causing an exaggerated reaction from the autonomic nervous system. Cold flashes make the individual feel as though they are freezing, even in a warm environment.
  • Uncontrollable Leg Movements: Uncontrollable leg movements, or restless leg syndrome, is a symptom that causes involuntary movements or twitching of the legs, particularly when the individual is resting or attempting to sleep. The sensations are uncomfortable, and individuals feel an irresistible urge to move their legs, which interferes with rest.
  • Intense Cravings: Intense cravings mean the uncontrollable urge to consume heroin. These cravings are one of the main triggers for relapse.
  • Suicidal Thoughts: Suicidal thoughts are the emotional and psychological strain of heroin withdrawal that leads to feelings of hopelessness, depression, and despair. These emotions become so overwhelming that individuals experience suicidal thoughts. The lack of the drug’s euphoric effects magnifies pre-existing emotional issues and leads to a sense of desperation.

What are the Positive Effects of Heroin?

The positive effects of heroin are intense euphoria, pain relief, and a sense of relaxation. The positive effects of heroin feel good in the short term, which is why individuals turn to the drug in the first place. These effects are not truly “positive” in a long-term sense, as they mask underlying issues and come with significant risks. The immediate relief and pleasure that heroin provides are fleeting and come at a high cost of dependency, severe physical and mental health deterioration, and the potential for overdose. The initial “positive” feelings are what drives the cycle of addiction, but they ultimately lead to long-term harm, showing that what feels good at the moment leads to devastating consequences.

What are the Health Risks Associated with Heroin?

The health risks associated with heroin use are overdose, organ damage, and mental impact. One of the most significant dangers is the potential for overdose, which occurs when the drug depresses the respiratory system to a life-threatening level. Overdose deaths in the US involving heroin have dramatically increased, with over 9,173 deaths in 2021, and 5,871 reported deaths in 2022., according to the research titled “U.S. Overdose Deaths Involving Heroin, by Other Opioid Involvement, 1999-2022.” The highly addictive nature of heroin quickly leads to tolerance, higher doses, and ultimately fatal respiratory depression. Long-term heroin use significantly reduces life expectancy, because it is linked to numerous health complications, including liver disease, heart infections, and irreversible brain damage. Heroin negatively impacts physical health, making it one of the deadliest substances in terms of both immediate overdose risks and long-term health consequences.

What is Heroin Addiction?

Heroin addiction is a chronic, relapsing condition characterized by the compulsive and uncontrollable use of heroin despite harmful consequences. Heroin addiction is a type of substance use disorder that develops when the brain becomes dependent on heroin to function normally, particularly due to its powerful effects on the brain’s reward system. Addiction occurs when a person’s behavior is dominated by the need to obtain and use the drug, leading to tolerance, withdrawal symptoms, and an inability to stop use even when it leads to physical, emotional, and social harm according to the research titled “Drug addiction (substance use disorder)” published by Mayo Clinic. Heroin addiction is not just a physical dependence but also a psychological compulsion to continue using the drug to avoid withdrawal symptoms and maintain a sense of euphoria.

What are the Treatment Options for Heroin Addiction?

The treatment options for heroin addiction are a combination of medical, therapeutic, and support-based approaches designed to help individuals overcome their dependency. Heroin addiction treatments include medication-assisted treatment (MAT), which utilizes drugs like methadone, buprenorphine, or naltrexone to reduce cravings and withdrawal symptoms. Detoxification is the first step that helps the body safely clear heroin from the system under medical supervision. Behavioral therapy, like cognitive-behavioral therapy (CBT) or contingency management, addresses the psychological aspects of addiction by helping individuals identify triggers and develop coping strategies. Support groups provide ongoing emotional and social support through shared experiences.

What is Heroin?

Heroin is a highly addictive opioid drug derived from morphine, which is found in the opium poppy plant. Heroin is used for its euphoric effects, but it is illegal and poses significant health risks. Heroin can be injected, snorted, or smoked, and it quickly crosses the blood-brain barrier, leading to intense pleasure. Some people initially use heroin recreationally, but its potent addictive properties lead to dependence, overdose, and a range of severe health complications, including organ damage and respiratory depression. Heroin use is associated with a high risk of overdose, and regular use significantly reduces life expectancy.

What Does Heroin Feel Like?

Heroin feels like a rush of euphoria after consumption, followed by relaxation, pain relief, and a sense of happiness, but it also causes drowsiness and clouded mental functioning.

What are the street names of heroin?

Street names for heroin include Smack, horse, H, dope, junk, and China White. Other terms such as black tar describe its dark, sticky form, while brown sugar refers to its powdery appearance.

How Does Heroin Work in the Body?

Heroin works in the body by entering the brain and binding to opioid receptors, altering brain chemistry, and producing pain relief, euphoria, and sedation. Heroin disrupts the brain’s natural production of endorphins, leading to dependency as the body begins to rely on the drug for these sensations.

Can you smoke Heroin?

Yes, you can smoke heroin. The smoking method involves heating heroin on foil or another surface and inhaling the vapors through a straw or tube. Smoking heroin allows the drug to enter the bloodstream through the lungs, leading to fast absorption and effects similar to injection.

How Long Does Heroin Take to Kick In?

Heroin takes effect within 7 to 8 seconds when injected, or 10 to 15 minutes when snorted or smoked.

Can Heroin Cause Overdose?

Yes, heroin can cause an overdose, which is often life-threatening. A heroin overdose occurs when a person takes a dose of heroin that overwhelms the body’s ability to process the drug, leading to slowed or stopped breathing, unconsciousness, and even death.

Are Heroin Side Effects Similar to Other Drugs?

Yes, heroin side effects are similar to those of other drugs, particularly opioids like fentanyl and methadone. Fentanyl causes intense euphoria, pain relief, and respiratory depression, though fentanyl is much more potent, increasing the risk of overdose like heroin. Methamphetamine (meth) also shares some effects, such as euphoria and increased energy, but unlike heroin, meth is a stimulant and causes increased heart rate, anxiety, and agitation.

How Do Heroin and Meth Differ in Their Effects on the Body?

Heroin is a depressant that slows the central nervous system, causing pain relief, euphoria, and respiratory depression. Crystal meth is a stimulant that boosts energy, alertness, and heart rate, often leading to cardiovascular issues and anxiety. Both heroin and crystal meth are addictive, but heroin mainly causes sedation, while meth leads to hyperactivity and agitation.

Is Fentanyl Considered More Dangerous Than Heroin?

Yes, fentanyl is considered more dangerous than heroin. Fentanyl is more powerful, about 50 to 100 times stronger than heroin which greatly increases the risk of overdose, even from small amounts. Heroin and fentanyl both drugs cause respiratory depression and death, fentanyl’s high potency and the difficulty of measuring safe doses make it especially lethal.

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Published on: July 12th, 2016

Updated on: January 6th, 2025

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