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Buspirone HCL Doses For Different Patients

White Pills On A Wooden Table

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Buspar pill is commonly prescribed to relieve anxiety. Buspar dosing varies greatly from person to person according to the age group and the mental status of the patient. Appropriate Buspar dosages can only be prescribed by a licensed healthcare professional.

This article serves as an informational guide about the variety of  Buspirone doses, dosing regimen for each age group, and general rules on how to properly take the medicine.

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Learn More About Buspirone Dosage:

Available Dosage Formulations

Buspirone class is anxiolytic. It was first approved by the FDA in 1986, and since then, it is being used for the treatment of Generalized Anxiety Disorder (GAD). However, recently, there has been a Buspirone shortage in the US market. Buspar tablets are available in oral formulations only with dosages of:

  • 5 mg
  • 10 mg
  • 15 mg
  • 30 mg

Each Buspar pill contains an active ingredient and inactive elements, such as lactose, sodium starch glycolate, colloidal silicon dioxide, microcrystalline cellulose, and magnesium stearate. Iron oxide is present exclusively in the pill containing Buspirone 30 mg. The amount of active ingredient in each tablet is as follows:

Active Ingredient 
Buspirone strengthThe active ingredient in each pill
5 mg4.6 mg
10 mg9.1 mg
15 mg13.7 mg
30 mg27.4 mg

Buspar Tablets

Buspar 5 mg and 10 mg tablets are available as white, ovoid rectangular, or barrel-shaped pills which are scored for easy bisection. Whereas 15 mg strength is available as white pills, scored for a convenient bisection and trisection.

Always check the tablets before taking the medicine. If one has any suspicion about the drug being fake – it is imperative to notify the vendor about the issue.

Therefore, a Buspirone 5 mg tablet can be taken as 2.5mg and a 10mg  pill can provide two doses of 5 mg each. 15 mg tablet presents four dosage options:

  1.     Whole tablet – 15 mg
  2.     ⅔ tablet – 10 mg
  3.     ½ tablet – 7.5 mg
  4.     ⅓ tablet – 5 mg

30 mg Buspirone pills are available in pink color, with scoring for bi- or trisection, giving doses of 30 mg, 20 mg, 15 mg, and 10 mg.
Woman Takes Oral Prescription Medication

Recommended Pediatric Dosage

The use of the medication is not indicated for infants. However, for children, studies are still underway to determine the effect of Buspirone in this age group.

Pre-adolescents

2.5 to 5mg per day, orally.

The dose can be increased by 2.5mg after every 3-4 days with a maximum Buspar dosage limit of 20mg/day.

Adolescents

5 to 10 mg per day

Allowed increments are of 5 mg/day at weekly intervals, as needed, without exceeding the max Buspar dose of 60mg/day per day.

As of now, there are no unexpected Buspar adverse effects among the pediatric population.

Recommended Dosage For Adults

For adults diagnosed with anxiety, the initially recommended daily dose is 10 to 15mg per oral (PO), in two to three divided doses. This means that a 15mg Buspirone pill can be taken in a day as 7.5mg b.i.d PO. An increment of 5mg per day can be made every 2-3 days to reach an optimal therapeutic response, as needed. The increment should not go beyond the dosage limit of 60mg per day.

Having said that, since Buspirone is a slow-acting anxiolytic, it may take 2 to 4 weeks for its beneficial effects to surface. So, how does Buspirone make one feel upon taking it? Usually, patients experience anxiety relief that may be accompanied by drowsiness.

Using more than the recommended dosage may lead to adverse reactions of different severity. Do not change the dosage without permission from the physician

Recommended Dosage Аor Geriatrics

Since the renal and hepatic impairment is commonly seen in the geriatric population, careful dosing is recommended, starting with the lowest possible Buspar dosage. Usually, 5 mg is given orally twice a day, with a gradual increase of up to 5mg per day after every 2-3 days, as needed, without surpassing the max dosage of 60mg per day
Mature Woman In Glasses

Dose Adjustments

Some modification in the Buspirone dosing is advised in patients with liver and renal dysfunction, as these conditions increase the half-life of Buspar. Although specific dose adjustment recommendations are lacking, clinical judgment is used to govern the adjustment of doses according to the extent of impairment.

Therefore, mild renal impairment requires no dose adjustments, whereas, with moderate kidney dysfunction, it is recommended to start with a lower Buspirone dose, then adjust according to the clinical assessment. Similar are the recommendations for mild to moderate liver dysfunction.

Buspirone is strictly not recommended with severe renal or hepatic impairment. Also, Buspar and alcohol together must not be used as it’s abuse can lead to an overdose, coma, or even death.

As for sexual dysfunction, there are no recommendations for dose modification. So, does Buspirone cause erectile dysfunction? No, in fact, it helps to reverse the erectile dysfunction caused by other medications, like SSRIs.

Self-prescription and self-medication are dangerous for one’s health and quality of life.

Buspirone And Food

Patients should take a Buspar tablet at the same time each day, and consistently either always with or without food. It is recommended to take it with food as it increases the bioavailability of Buspirone.

Missed Dose

It is advised to take the missed dose as early as the patient realizes. However, if it’s close to the time of the next dose, the missed Buspar dose should be skipped. It is strongly not recommended to take two doses together to make up for the missed one.

Taking Buspar as needed is permitted. However, if more than one dose is missed or the existing doses seem to be ineffective, it’s best to consult with the prescribing physician rather than autonomous changes.

Adhering To The Dosage Instructions

It is important to follow the doctor’s instructions for Buspirone HCl. The violation of dose regimen and safety instructions may result in Buspar side effects and even health complications.

Though not addictive, it can still be abused. Therefore, patients who experience addiction to this medicine should look for professional assistance from local addiction treatment centers. Such facilities provide a range of customizable addiction treatment programs that will help the patient to recover from abuse and dependency.

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Sources
  1. Landén M, Eriksson E, Agren H, Fahlén T. Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors. J Clin Psychopharmacol. 1999;19(3):268-271. https://pubmed.ncbi.nlm.nih.gov/10350034/
  2. Wilson TK, Tripp J. Buspirone. [Updated 2020 Mar 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. https://www.ncbi.nlm.nih.gov/books/NBK531477/fbclid=IwAR3iojz0VcejfIiqwYwhPmJQyiFJM16BEWlxrdTvrr_A0Ver8-gPiyRb1b8
  3. Strawn, J. R., Mills, J. A., Cornwall, G. J., Mossman, S. A., Varney, S. T., Keeshin, B. R., & Croarkin, P. E. (2018). Buspirone in Children and Adolescents with Anxiety: A Review and Bayesian Analysis of Abandoned Randomized Controlled Trials. Journal of child and adolescent psychopharmacology, 28(1), 2–9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771537/
Isaak Stotts

About Author

Isaak Stotts, LP

Isaak Stotts is an in-house medical writer in AddictionResource. Isaak learned addiction psychology at Aspen University and got a Master's Degree in Arts in Psychology and Addiction Counseling. After graduation, he became a substance abuse counselor, providing individual, group, and family counseling for those who strive to achieve and maintain sobriety and recovery goals.

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