Skip to main content

Find Treatment Near You

Wellbutrin Hair Loss: Causes, Symptoms and Management Options

Medically Reviewed Sources cited Share
Brittni Edit by: BrittniDr. Norman Chazin Reviewed by: Dr. Norman ChazinMaría José Petit-Rodríguez Written by: María José Petit-Rodríguez
Wellbutrin pills And Hair Loss

As one of the most commonly prescribed antidepressant medications, millions of individuals rely on Wellbutrin to manage symptoms of depression, anxiety, and even smoking cessation.

Bupropion use has significant relevance for psychiatric medicine. While Wellbutrin is generally well-tolerated, it is not without its side effects. Users may experience common side effects such as insomnia, dry mouth, changes in appetite, and hair loss. In light of the potential for Wellbutrin hair loss, we will provide professional guidance, safety tips, and actionable strategies to help users minimize this side effect.

3 Clinical Reasons for Wellbutrin Hair Loss

“Can Wellbutrin cause hair loss?” is a common question that Wellbutrin users often ask their healthcare providers. Although the relationship between Wellbutrin and hair loss is not clear, and research on this specific side effect is limited, the increased risk of alopecia, particularly in the form of shedding while taking Wellbutrin, can be attributed to:

  • Wellbutrin Causes Hormonal Fluctuations

The increased risk of alopecia with Wellbutrin use may be attributed to a sudden change in hormone levels. Hormonal fluctuations, which can result from medication or other factors, impact hair follicles. These fluctuations can induce a resting state in the follicles, leading to alopecia, which may partially explain Wellbutrin hair loss.

  • Telogen Effluvium

Telogen effluvium is a form of temporary nonscarring alopecia categorized by diffuse, often acute hair shedding, and it’s been linked to antidepressants.

Among this class of drugs, Bupropion had the highest risk of alopecia where 95% of the users experienced shedding as an effect. Thus, the premise of Wellbutrin hair loss is correct. Women in particular, may experience widespread thinning and increased hair loss, especially during periods of stress or when adjusting to a new antidepressant. Yet, it’s safe to state that Wellbutrin hair loss is commonly reversible upon drug discontinuation.

  • Dose-Dependent Effect

Higher doses of Bupropion can intensify the occurrence of telogen effluvium in shorter periods. This suggests a potential dose-dependent relationship between Wellbutrin and hair loss, emphasizing the importance of carefully managing medication dosage.

When diagnosing drug-induced hair loss, it is essential to rule out other potential causes and consider the correlation between hair loss and the initiation of drug treatment or changes in Wellbutrin dosage.

Practical Approaches to Wellbutrin Hair Loss

Addressing Wellbutrin-related hair loss requires practical approaches focusing on overall hair health and the specific factors associated with this side effect. Here are practical strategies to manage Wellbutrin-induced hair loss:

  • Consultation with Healthcare Provider: Contact your healthcare provider to discuss your concerns about hair loss.
  • Nutritional Support: Maintain a balanced diet of essential vitamins and minerals. Consider incorporating foods high in biotin, iron, and other nutrients beneficial for hair growth.
  • Gentle Hair Care Practices: Use mild shampoos and conditioners to avoid excessive hair damage. Limit heat styling tools and be gentle when brushing.
  • Stress Management: Incorporate stress-reduction techniques such as meditation, yoga or deep breathing exercises to support well-being, including hair health.
  • Consider Hair Supplements: Consult with your healthcare provider about the potential benefits of hair supplements. Biotin supplements, for example, are often recommended for hair, skin, and nail health.

Bottom Line

While the answer to the common question, “Does Wellbutrin cause hair loss?” is yes. Fortunately, Wellbutrin-induced hair loss is often temporary. Hair growth should resume once the medication is discontinued or the body has adjusted to the dose. Patience and close monitoring during this process are crucial for safe and effective Wellbutrin use.

If you continue to experience concerns about hair loss and you want to stop the medication, remember to approach medication adjustments with caution. Abruptly discontinuing an antidepressant, including Wellbutrin, can lead to more severe Wellbutrin side effects beyond hair loss. Discontinuation should be done under the guidance of a healthcare professional to minimize potential risks.

People Also Ask

How common is hair loss with Wellbutrin?

Hair loss is considered a relatively uncommon side effect of Wellbutrin (Bupropion). While it’s listed as a potential adverse reaction in the medication’s prescribing information, not everyone who takes Wellbutrin will experience hair loss.

Is wellbutrin hair loss permanent?

Hair loss associated with Wellbutrin is generally not permanent. While some individuals may experience hair thinning or loss as a side effect, this is typically reversible. Hair growth usually resumes once the medication is discontinued or the dosage is adjusted. Please note that it is essential to discuss this side effect with your professional healthcare provider, as the timeline for regrowth can vary from person to person.

Which antidepressants are most likely to cause hair loss?

Hair loss can be a side effect of several antidepressant medications. Some of the antidepressants that have been associated with hair loss include selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac) and sertraline (Zoloft), as well as tricyclic antidepressants (TCAs).

Is Lithium hair loss reversible?

Lithium, commonly used for bipolar disorder, may cause reversible hair loss. Discontinuing the medication often allows hair growth resumption, but the extent of reversibility varies among individuals. Consult with a healthcare provider if experiencing this side effect.


Retrieved on february 27, 2024

Addiction Resource

Why Trust AddictionResource.com

Founded in 2014, Addiction Resource provides free support and guidance for addiction recovery.

Learn More ›

Start the road to recovery

Connect with an accredited treatment center by calling our admissions team directly.

Have a question? (866) 289-4139

Who Answers?

OR

Request A Call

Free Insurance Verification
Disclaimer: The information provided on this website is intended for educational and informational purposes only and should not be considered a substitute for professional medical care. If you or your loved one is experiencing an addiction crisis, please seek immediate expert guidance or contact emergency services.

Hope Without Commitment

Find the best treatment options. Call our free and confidential helpline

(866) 289-4139

Most private insurances accepted

Who Answers?

Find Drug Rehabilitation Centers Near You Anywhere In the US

Addiction Resource team has compiled an extensive list of the top drug rehabilitation facilities around the country. Use our locator tool to find the best centers near you.

Page Sources

  1. Fava, M., Rush, A. J., Thase, M. E., Clayton, A., Stahl, S. M., Pradko, J. F., & Johnston, J. A. (2005). 15 Years of Clinical Experience With Bupropion HCl: From Bupropion to Bupropion SR to Bupropion XL. Primary Care Companion to The Journal of Clinical Psychiatry, 7(3), 106-113.
  2. Clark, A., Tate, B., Urban, B., Schroeder, R., Gennuso, S., Ahmadzadeh, S., McGregor, D., Girma, B., Shekoohi, S., & Kaye, A. D. (2023). Bupropion Mediated Effects on Depression, Attention Deficit Hyperactivity Disorder, and Smoking Cessation. Health Psychology Research, 11.
  3. Vardanyan, R., & Hruby, V. (2016). Antidepressants. In Synthesis of Best-Seller Drugs (pp. 111-143).
  4. National Institute of Mental Health. (n.d.). Seasonal affective disorder. NIMH.
  5. Mooney, M. E., & Sofuoglu, M. (2006). Bupropion for the treatment of nicotine withdrawal and craving. Expert Review of Neurotherapeutics, 6(7), 965–981.
  6. Verbeeck, W., Bekkering, G. E., & Kramers, C. (2017). Bupropion for attention deficit hyperactivity disorder (ADHD) in adults. The Cochrane Database of Systematic Reviews, 2017(10).
  7. Berigan, T. R. (2002). The Many Uses of Bupropion and Bupropion Sustained Release (SR) in Adults. Primary Care Companion to The Journal of Clinical Psychiatry, 4(1), 30-32.
  8. Hasan, R., Juma, H., Eid, F. A., Alaswad, H. A., Ali, W. M., & Aladraj, F. J. (2022). Effects of Hormones and Endocrine Disorders on Hair Growth. Cureus, 14(12).
  9. Hughes, E. C. (2023, May 29). Telogen effluvium. StatPearls – NCBI Bookshelf
  10. Etminan, M., Sodhi, M., Procyshyn, R. M., Guo, M., & Carleton, B. (2018). Risk of hair loss with different antidepressants. International Clinical Psychopharmacology, 33(1), 44–48.
  11. Pitton Rissardo, J., Fornari Caprara, A. L., Casares, M., Skinner, H. J., & Alford, R. (2020). Bupropion and Hair Loss: A Case Report and Review of the Literature. Journal of Clinical Psychopharmacology, 40(4), 416-418.

Published on:

Updated on: