Lortab Alternatives: Is Percocet Stronger Than Lortab?

Last Updated: April 20, 2021

Authored by Olivier George, Ph.D.

Lortab medicine is used to relieve moderate to severe pain. While it serves as a reliable painkiller to a great extent, many individuals tend to get addicted to the opioids. Fortunately, there are OTCs and natural Lortab alternatives that one can consider. The substitutes to Lortab are easy to use, readily available, and also treat numerous health issues. Find the difference between Norco, Vicodin, other opioids, OTC, and natural alternatives to Lortab.

The Difference Between Lortab and Vicodin

Lortab, and Vicodin are very similar medications. Both of them are brand name opioids and provide similar pain-relieving effects.

Man Choose between Norco, Vicodin and Lortab

They both are opioid painkillers and available with a prescription. Since both of them contain hydrocodone, they have the ability to cause addiction. An individual should only consume Lortab 5mg to get relief from moderate to severe pain until a doctor changes the amount prescribed.
When it comes to Norco and Vicodin, the only difference between them is the proportion of the ingredients.

Opioid Alternatives To Lortab

According to the U.S. National Library of Medicines National Institutes of Health, opioids, both short and long-acting, are effective for treating injury. They are often used to manage chronic noncancer pain. They can also be used for patients with chronic low back pain who do not respond to NSAIDs or acetaminophen agents. Here are some of the opioid alternatives that one can consider if the current medication fails to provide adequate analgesia.

Man is holding a few medicine blisters

Lortab Vs. Oxycodone

Both of them provide the same level of relief. On average, they both take about half an hour to show effects.

Percocet Vs. Lortab

Lortab Vs. Tramadol

Tramadol is a bit milder than the particular opioid. Both drugs affect brain receptors, but Tramadol also enables chemical passengers to remain in the brain for an extended duration. The potential of addiction for both is less but is still a risk.

Trezix Vs. Lortab

Trezix comes with dihydrocodeine and acetaminophen. Both of them are strong painkillers, but Trezix is a cardiovascular stimulant, narcotic analgesics, which provides relief from moderately severe pain.

Hycet Vs. Lortab

It also works as a combination of medicine and is used to relieve moderate to severe pain and have a similar pros and cons.

Darvocet Vs. Lortab

Darvocet is a combination of propoxyphene and acetaminophen. The patient can use it to get relief from mild to moderate pain that comes with or without fever.

Demerol Vs. Lortab

Demerol is mainly used to treat post-surgical injuries. But it produces a toxic product in the body that can cause seizures and tremors.

Nucynta Vs. Lortab

Nucynta is used for both acute and chronic pain. Due to its immediate and extended-release formulation, it is prescribed for pain related to diabetic neuropathy.

Lortab OTC Alternatives

U.S. Food & Drug Administration found that Over the Counter medicines are safe and effective to use. Moreover, OTCs are readily available and less expensive. Now according to a 2018 Morbidity and Mortality report, 20.4% of patients complain about chronic pain, and 8.0% of adults suffer from high impact chronic pain. To get the relief, users can consider some OTC alternatives instead opioids.

  • Acetaminophen: This OTC does not need a prescription and is known to be good at relieving back pain and headaches.
  • Ibuprofen: OTCs such as Tylenol are also a good choice for treating mild to moderate pain. Lortab and ibuprofen can also be used together for short term relief of pain.

Natural Alternatives

While this opioid medication is prescribed to relieve moderate to severe pain that is associated with conditions like back pain, arthritis, and physical injury and should be used only as short term treatment, those who are looking for help with mild to moderate pain may ask the doctor about the natural painkillers. Sometimes they can be as effective as prescription medication but come with some side effects.

Lortab natural alternatives
Here are some of the Lortab natural alternatives that one can consider:


While it is not an opiate, Kratom can decrease pain and fatigue. According to the National Institute on Drug Abuse, Kratom is also known to cause effects similar to both opioids and stimulants. In small doses, it produces stimulating effect whereas; the larger doses can lead to sedation. If an individual chooses to use Kratom, do it only under a doctor’s supervision, because it still falls under drugs of concern category, according to DEA.

Valerian Root


Cayenne pepper can be used to treat joint pains. An individual can also apply it on the skin as it distracts the brain for underlying pain.

Willow Bark

It is known as one of the most effective anti-inflammatory herbs; it comes with the same active compound as aspirin. It is usually used to treat inflammatory pains that are associated with toothache, minor injury, burns, or cuts.

What Is The Best Lortab Alternative?

Before a patient chooses to continue with any of the above-mentioned alternative or Lortab generic versions, consult an experienced doctor who can determine the level of pain and suggest the best and safest alternative for the same.
In case, if somebody has consumed this painkiller for prolonged periods, there is always a risk of withdrawal symptoms to appear. The withdrawal will start between 6 and 12 hours after the last dose. However, the Lortab withdrawal timeline can go up to 72 hours and last for a few weeks. So, a specific alternative can be provided to patients during this period.
Remember that, like any other opioid, this one also has the hidden risk to become addicted to. It also leads to various side effects, such as anxiety, depression, mood swings, and more. If someone is dealing with Lortab addiction, there are many treatment programs that can help an individual to overcome addiction and any co-occurring health disorders. Don’t hesitate about asking for help in a professional addiction treatment center.

Page Sources

  1. Charles E. Argoff, Daniel I. Silvershein, A Comparison of Long- and Short-Acting Opioids for the Treatment of Chronic Noncancer Pain: Tailoring Therapy to Meet Patient Needs, www.ncbi.nlm.nih.gov/pmc/articles/PMC2704132/
  2. NIDA, Kratom, https://www.drugabuse.gov/publications/drugfacts/
  3. United States 
Drug Enforcement Administration, Kratom, https://www.dea.gov/factsheets/kratom

Published on: July 30th, 2019

Updated on: April 20th, 2021

About Author

Olivier George, Ph.D.

Olivier George is a medical writer and head manager of the rehab center in California. He spends a lot of time in collecting and analyzing the traditional approaches for substance abuse treatment and assessing their efficiency.


Leave a comment