The Optimal Dose Of Vyvanse: Dosage For Adults And Kids

Last Updated: January 21, 2021

Authored by Isaak Stotts, LP

Reviewed by Michael Espelin APRN

Many patients struggle with understanding what the drug Vyvanse is used for and its required dose. In most cases, there are strict dosages for a particular condition. Still, every situation is different, and it is important to be aware of the exceptions.

Vyvanse Dosage: General Information

There are a lot of factors to be considered when choosing a Vyvanse dose. It is a stimulant drug; scientific name is lisdexamfetamine dimesylate. Patients should make sure their doctors pay attention to their weight, age, height as well as the condition being treated. Vyvanse dosage by weight offers a more accurate reading and offers more effective results as well.

No matter what the condition, it’s critical that patients start low with their dosage and work up to a moderate or high dose over time. Patients are advised to speak with their medical care professionals about different dosing options first and talk with them about how to get started with a treatment plan before doing something like deciding to buy Vyvanse online.

Vyvanse Dosage For Adults

Adults need to work with a medical professional to determine the lisdexamfetamine dosage that is right for them. Commonly, they take from 30 mg to 70 mg Vyvanse depending on their disorder. Some patients dissolve Vyvanse in water to determine their perfect dose of medication. In certain cases, the starting dosage can be increased up to Vyvanse 40 mg dose and move up or down from there as needed. Still, the starting amount depends on a patient’s conditions and the prescribed treatment.

Vyvanse Dosage For Children

boy taking vyvanse pillDosing for children (6-year-old and above) is almost the same but still differs from lisdexamfetamine dosage for adults. Children can benefit from the lowest dose of Vyvanse. It is common to start with Vyvanse 30 mg per day; however, in some cases, 20 mg as an initial dose is prescribed. At each dose level, the medication should be closely monitored. At the same time, the higher dosages are utilized with as much as 70 mg given out per day. Everyone reacts with medications differently, which is why children must be assessed carefully, started with a low dose and gradually adjusted from there.

Dosage For ADHD

Lisdexamfetamine is an FDA-approved medication for treating patients suffering from ADHD. Both adults and children alike can use medicine to help alleviate symptoms of ADHD, but their Vyvanse dosage may differ. Adults are often given between 40 and 50 mg for treatment. The gradual increase of dose is 10-20 mg at weekly intervals. The Vyvanse max dose for adults with ADHD is 70 mg per day, but it’s rare for that much to be prescribed as an initial dose. At the same time, even 50 mg of Vyvanse may cause high which is an undesirable effect of the drug.

Dosage For BED

BED is a severe condition that affects millions of people worldwide each year. The condition may be treatable using Vyvanse, and the highest dosage of lisdexamfetamine has been found to work best for treatment in recent studies. Taking at least 30 mg dosage per day can help with reducing binge eating episodes. Additionally, going for a higher level on the Vyvanse dosage chart such as 50 mg or 70 mg has been shown to work even better. For those who pass a drug test, information on how long Vyvanse stays in urine can be useful.

Contradictions And Cautions

Those patients who experience severe cardiovascular diseases or have a cardiovascular medical history, including Coronary Artery Disease (CAD), cardiomyopathy, severe arrhythmias, and cardiac structural abnormalities, need to consult with a doctor what dose of Vyvanse they need to take, if any. The conditions mentioned above may require Vyvanse alternatives.

doctor using a Vyvanse dosing chart to weight health risksIt’s entirely reasonable to experience some side effects of Vyvanse. However, if a dosing chart used correctly, there can be only a few. Otherwise, a wrong determining of how much medication to take for particular condition poses serious complications, including Vyvanse effects on sex drive.

Doctors advise their patients to be careful and always use the medication properly. Nobody should snort Vyvanse, as it is designed primarily for oral intake. Also, there is no need to figure out how to make Vyvanse stronger. Any self-increase in doing can be dangerous.

Dosage Decrease

It is also highly unrecommended to decrease dose abruptly if a patient uses a high dosage of medication during a long period. Furthermore, such conditions as glaucoma, psychosis, Tourette syndrome, and HTN should be considered by a doctor when prescribing a lisdexamfetamine dose. Before mixing Vyvanse and Xanax or other drugs and substances, it’s important to get medical consultation to avoid undesirable interactions.

Vyvanse Dosage For Patients With Renal Impairment

Patients with renal impairment must be cautious when taking lisdexamfetamine because the medication has a risk of building up in the body. This can lead to complications. Patients should discuss kidney disorders with their doctor, and anything higher than a 50 mg Vyvanse dose is not recommended for these patients. In the case of ESRD, users are advised to keep their highest dosage of Vyvanse 30 mg for best results and to consult closely with their doctors to avoid complications, as everything higher can make lisdexamfetamine fatal.

Renal Dosing

Disease Stage Mild-mod impairment Severe impairment End-stage renal disease (ESRD)
Maximal Dose not defined 50 mg/day 30 mg/day

Lethal Dose

The LD50 for the medication was established through testing on rats, coming in at 7,060 mg per kilogram of weight. That comes in at 100 70 mg pills—the strongest lisdexamfetamine dimesylate pill available. For an average adult weighing 80 kilograms, that would mean taking 8,000 70 mg Vyvanse capsules to reach the LD50.

Based on those numbers, few people would ever have access to how much Vyvanse is needed to overdose. However, amphetamines often behave unexpectedly, and overdoses can occur at levels much lower than the established LD50 dose.

Always Stick To The Prescribed Dose

Lisdexamfetamine is a powerful medication for treating ADHD in adults and children and can help with disorders like BED as well, but it’s essential to get the right Vyvanse dose during use to avoid complications. That often means beginning with the lowest dose of Vyvanse and increasing it slowly over time toward the highest dose required. With careful guidance from a medical professional and a systematic approach, a lisdexamfetamine prescription can offer a good mix of benefits. However, if one experiences the adverse health effects taking Vyvanse, it is important to get a doctor’s consultation on treatment options and rehabilitation centers if the drug is abused.

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Published on: April 1st, 2019

Updated on: January 21st, 2021

About Author

Isaak Stotts, LP

Isaak Stotts is an in-house medical writer in AddictionResource. Isaak learned addiction psychology at Aspen University and got a Master's Degree in Arts in Psychology and Addiction Counseling. After graduation, he became a substance abuse counselor, providing individual, group, and family counseling for those who strive to achieve and maintain sobriety and recovery goals.

Medically Reviewed by

Michael Espelin APRN

8 years of nursing experience in wide variety of behavioral and addition settings that include adult inpatient and outpatient mental health services with substance use disorders, and geriatric long-term care and hospice care.  He has a particular interest in psychopharmacology, nutritional psychiatry, and alternative treatment options involving particular vitamins, dietary supplements, and administering auricular acupuncture.


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