Phenibut Dosage: How Much Noofen To Take Safely

Last Updated: June 10, 2020

Authored by Roger Weiss, MD

Phenibut, a derivative of the GABA inhibitory neurotransmitter, is being sold as a supplement, making people use it under the erroneous assumption that no care is required regarding the Phenibut dosage. Unfortunately, Phenibut overdose is possible and causes significant sedation and impairment.

Clinically Approved Phenibut Dosage

In the US and other countries, the drug is legally available as a nutritional supplement as long as there are no claims made publicly to counter FDA guidelines. Anyone can find it online as Fenibut, Anvifen or Noofen.
Because scientific information is limited, it is difficult to determine an appropriate and approved Phenibut dosing.

Generally Accepted Phenibut Dosage

Doses under 1g are used for a lifestyle and cognitive supplement, while higher doses are for a recreational Phenibut high, similar to alcohol, GHB or benzodiazepines.
phenibut capsulesThe oral light Phenibut HCI dosage is between 250 mg and 750 mg, for common is between 750 mg and 1500 mg and for a high between 1500 mg and over 2000 mg. The Phenibut FAA dosage is between 500 mg and 1250 mg for common use.
This drug has a slow onset, which varies from one hour and a half to three or even four hours. Its effect lasts for four to ten hours, sometimes even more. Because of the slow onset, many people are prone to Phenibut redosing, which can easily lead to an overdose.

Dosage Recommendations For First-Time Users

Finding the optimum dosage is more a process of trial and error. Finding the right Phenibut dose depends on the user’s age, weight, and health.
For first-time users, the recommended dose is 500mg and gradually increase it from there to reach the desired results. Although a low dose might not offer significant or immediate results, it is better to have a safe start.

Starting dose Average dose High Dose
Therapeutic dose 250 mg to 750 mg 1000 mg to 1500 mg 1500 mg to 2000 mg (recreational)
For anxiety 750 mg to 1200 mg 1200mg to 1700 mg Up to 2700mg
For stress 750mg 1000 mg to 1500 mg Up to 2000 mg
For sleep 500 mg to 1200 mg 1200 mg to 1800 mg 1800mg to 2700mg

(severe insomnia)

Remember that a high-risk dose is between 2000 mg and 3000 mg.

How To Take Phenibut

Taking Anfiven capsules

Fenibut can be found under the form of tablets with various concentration or as a powder. When it comes to capsules, the dosage is predetermined, so the consumer only chooses what concentration they have. Simply take the pill, and that’s it.

Take Phenibut on an empty stomach for faster absorption and then wait at least 30 minutes before eating.

How to take Phenibut powder

When it comes to powder, things change a lot. The powder can be ingested in multiple ways.

One of the methods is to measure the desired quantity of powder, toss it into the back of the mouth and take a sip of water to swallow it. Then drink more water to wash any Fenibut that might be left in the mouth.

Another method is to take the desired quantity of the drug and mix it with water in a glass until it dissolves completely. Drink the entire glass of water. Fruit juice can also be used to hide the sour taste of the powder.

Phenibut Dosage Warnings And Precautions

Do not mix this drug with alcohol, as both of them increase the GABA activity in the brain, causing sedation. By combining them, the effects are intensified, increasing the risk of overdose, mental disturbances, loss of consciousness and Phenibut addiction.

Other warnings:

  • Do not take more than 1500 mg – 2000 mg per day
  • Do not use as an everyday supplement
  • It should be avoided by pregnant or breastfeeding women
  • Do not take a dose more than three times a week
  • Do not take while operating motorized vehicles

Signs And Symptoms Of Phenibut Overdose

Because no one knows which is the best way to take Phenibut until they try various methods, it is straightforward to take a higher dose than they should. Also, because it makes a few hours before starting to see the effects of the drug, the mistake of redosing Phenibut is quite frequent and can easily lead to an overdose.

woman feeling drowsyPhenibut overdose symptoms include:

  • Drowsiness
  • Bradycardia
  • Confusion
  • Cognitive impairment
  • Respiratory depression
  • Hypothermia
  • Hypotension
  • In some cases even coma
  • Falling asleep at random
  • Impairment of motor skills seen at alcohol intoxication.

Other possible effects of overdose are:

  • Bizarre uncontrolled behavior
  • Agitation
  • Delusions
  • Hallucinations
  • Mydriasis.

It is usually associated with low blood pressure and heart rate, but there have been cases of tachycardia and hypertension too.

Dangers Of Taking Too Much Phenibut

The biggest threat is overdosing, which can end up in a coma and the need for ICU hospital admission.

When taken regularly the drug can cause dependence and withdrawal symptoms may install when trying to quit it. Once the body has built a tolerance to Fenibut and physical dependence has been established, more and more substance will be needed for the same effect, making it even harder to stop taking it.

Other complications of Phenibut heavy use include eosinophilia and fatty liver disease. The liver being under constant attack from the drug, it continuously works to rid the body of it, not having enough time to repair itself. Eosinophilia is a condition which occurs when a large number of eosinophils white blood cells are necessary to fight an allergy to a compound of the drug. Some of the symptoms include night sweats, weight loss, skin rashes, lymph node enlargement and tingling or numbness due to nerve damage.

Treating Phenibut Overdose

emergency care doctors with patientA Fenibut overdose is a medical emergency which needs immediate medical assistance. Offer as much accurate information to the medical staff, to address the overdose correctly. The course of treatment may include gastric lavage, activated charcoal to bind the substance and prevent absorption, symptom-based treatment and the induction of vomiting.

The person will also have a full review made, a psychological assessment and blood samples taken. Once discharged, the patient’s progress will be checked with a follow-up appointment, and a referral for substance abuse treatment will be provided if needed.

Can One Die From Taking Too Much Noofen?

When taken too much, dangers include delirium, tonic-clonic seizures, and unconsciousness, but so far, there have been no reports linking an overdose with death.

Usually, an overdose should resolve itself significantly in no more than 24 hours.

In conclusion, Phenibut buy is available to anyone who has access to the Internet, with no control whatsoever. Because the Fenibut abuse dangers are severe and can severely impact health, one should be careful about the dosage. Medical help is of utmost importance in the case of an overdose or addiction, and many drug rehab facilities are available for those who have developed dependence. The treatment for individuals with addiction to this nootropic drug can change the life for good.

Page Sources


Published on: April 10th, 2019

Updated on: June 10th, 2020

About Author

Roger Weiss, MD

Dr. Roger Weiss is a practicing mental health specialist at the hospital. Dr. Weiss combines his clinical practice and medical writing career since 2009. Apart from these activities, Dr. Weiss also delivers lectures for youth, former addicts, and everyone interested in topics such as substance abuse and treatment.


Leave a comment