It is a habit-forming chemical which you can find in various tobacco products. They include cigarettes, cigars, electronic cigarettes, tobacco chew or snuff. Smoking reduction/cessation products such as patches, gums, and lozenges also contain it.
You are not likely to overdose on it just by smoking. However, they have reported some cases of overdose in kids who accidentally ate it. Even a small amount can cause lots of problems.
Factors That Affect The Severity Of Nicotine Overdose
There are two prime factors that determine if an amount of Nicotine will produce toxic effects. They are body weight and its source.
In general, higher the body weight, greater the amount you need to produce the symptoms of overdose.
Likewise, tobacco products such as e-cigarettes can pose a greater risk. This is because they contain a liquid form of Nicotine. Therefore, it’s more potent and more likely to cause harm even with a small amount.
Other products such as lozenges and gums are very dangerous. This is because of their inviting appearance. In fact, kids may mistake some of them for candy or chewing gum. As a result, this leaves them vulnerable to dangerous levels in their blood.
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Nicotine Overdose Symptoms: A Two-Phase Rollercoaster
Phase I Excitation: It can happen as early as 15 minutes to one hour after ingestion or inhalation. This is when early symptoms of overdose may manifest. If the overdose is mild, the symptoms may last for up to two hours.
However, with heavy poisoning, they may last for more than 24 hours. The symptoms of early Nicotine overdose may include:
- Abdominal cramp
- Restlessness or over-excitement
- Increased salivation
- Rapid breathing
- Elevated blood pressure
- Muscle twitches
- Mental confusion
- Racing heartbeat
Phase II Depression: During the next 30 minutes to four hours, the overall body functions slow down. The typical Nicotine overdose symptoms in this phase include:
- Diarrhea or loose motion
- Superficial breathing
- Reduced blood pressure
- Slowed pulse or heartbeat
- Loss of control over muscle movements or reflexes
How Nicotine Overdose Affects Your Body/Brain
Nicotine possesses mind-altering properties. This is by the virtue of its ability to change the levels of brain chemicals. Being an oil-soluble substance, it reaches the brain rapidly after eating or smoking.
The chemical exerts its effects by mimicking the activities of a brain chemical. Scientists call it acetylcholine (ACh). This is after it reaches the brain. ACh is an important functional component of the nervous system. It has a widespread role in muscle movement, breathing, heartbeat, memory, and learning.
Additionally, it boosts the level of another mood-enhancing brain chemical. They call it dopamine. Having high levels of dopamine in the brain gives you the feelings of pleasure and reward. This is the reason why quitting smoking is such a tough task.
When you overdose, the first set of symptoms is mainly excitatory in nature. However, within some hours, the nicotine binding sites in the brain will become full. After this excitation plunges, the symptoms of depression begin to manifest.
How Much Nicotine Does It Take To Overdose?
The dosage you need for nicotine overdose is way higher than what you get by smoking or chewing tobacco. Thus, it is quite unlikely that smoking or chewing can turn fatal. This is even when you try to overdo it.
Still, you can consume fatal doses through other sources. They include e-cigarettes, nicotine gums, and lozenges.
An average adult needs to consume at least 50 to 60 mg of nicotine to develop overdose symptoms. This is according to the Centers for Disease Control and Prevention (CDC).
Are you planning to poison yourself with nicotine? You would need to smoke at least two packs continuously. This is considering a cigarette contains only 1mg of it.
This doesn’t seem possible even when you attempt to poison yourself on purpose. Yet, for the kids, even the nicotine inside a single cigarette may be toxic. Be aware of Nicotine addiction signs to prevent overdose.
In any case, what determines the toxicity is how much nicotine reaches your brain.
Nicotine Overdose Death
Death due to Nicotine overdose is very rare. Sometimes, people ingest pesticides that contain nicotine. This only comes from cases people report. Almost all the cases of death from nicotine overdose have been from this. Also, the overdose include both accidental and intentional.
Nicotine Overdose Treatment
There is no known antidote to treat nicotine overdose. Available medications help to improve the overdose symptoms and ease the recovery. An immediate treatment produces successful results in almost every case of overdose.
The medications that provide supportive treatment include:
- Activated charcoal – if the patient is conscious and able to take it by mouth. Also, this treatment is more effective if the time of Nicotine overdose has not gone beyond a few hours. This may help to reduce its absorption inside the digestive tract.
- Benzo to control seizures
- Fluid and salt injection to treat low blood pressure
- Atropine – This is a naturally occurring chemical. It acts against the activities of ACh to treat slowed pulse
- If breathing is very slow, the doctor may recommend artificial ventilation. It will support natural breathing.
What You Should Do To Help Someone Having Nicotine Overdose
Do you or someone you know have Nicotine overdose? Call your local emergency number 911. Or call the national toll-free Poison Help hotline (1-800-222-1222). You can reach it from anywhere in the United States.
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