How Long Does Fioricet Stay in Your System?

Addiction Resource > Addictive Substances: The Anatomy of Drug Addiction > Fioricet Addiction and Treatment > How Long Does Fioricet Stay in Your System?

How Long Does Fioricet Stay in Your System?

Can drug tests detect Fioricet?

Yes. Although testing for Fioricet is not common, some tests can find the drug in your system, and your results can show positive for barbiturates. That’s because Fioricet contains Butalbital, Acetaminophen, and Caffeine; and Butalbital is an intermediate-lasting barbiturate. For instance, an EIA test (the immunoassay technique), can detect Fioricet for up to 72 hours.

How long does Fioricet stay in your system?

Fioricet can remain in a person’s system for up to 4-5 days. However, many factors affect that: overall health of the user, dosage, history of abuse, and of course, metabolism rates. Note that the half-life of Butalbital is 35 hours, of acetaminophen- 1-3 hours, and of caffeine– around 3 hours. Urine tests can detect Fioricet for up to seven days.

Fioricet, or the combination of Butalbital, acetaminophen, and caffeine, is usually used for the treatment of tension and unbearable headaches. That might sound harmless but remember that the drug can lead to severe consequences for the user. One of the potential risks is that Fioricet can show up on a drug test, which can result in job loss.

Fioricet stays in one’s system for up to 4-5 days.
Addiction professional with a phone

Hope Without Commitment

Find the best treatment options.Call our free and confidential helpline

Factors That Influence the Duration & Elimination of Fioricet

Like any other drug, we can’t say how long Fioricet will stay in your system as many factors affect the duration and elimination of the drug.

  • Dosage and history of abuse
  • Individual factors (weight, age, overall health)
  • Metabolism rates
  • Lifestyle (activities, food intake, other drugs)

How Is Fioricet Metabolized?

As Fioricet is a combination of 3 separate drugs, we should explore the ways the body metabolizes each one of these drugs:

fioricet pills

Butalbital: This barbiturate is absorbed by the gastrointestinal tract, with a half-life of 35 hours. Elimination of the drug happens via the kidneys. Some metabolites can also be present in the urine sample.

Acetaminophen: The plasma half-life of acetaminophen is between 1 and 3 hours, and the elimination of the drug is by liver metabolism, followed by renal excretion of different metabolites. Acetemenephine is very hard on the liver for this reason and may cause liver failure.

Caffeine: Caffeine is rapidly absorbed by the body, with a plasma half-life of around 3 hours. The drug clears through the urine. It’s interesting to mention tests may find metabolites, but find only 3% unchanged caffeine.

Fioricet Half-Life & Duration of Action

One can feel the analgesic effects of Fioricet within 2 hours. These effects last between 4 and 6 hours.

As stated above, Butalbital has a long half-life (35 hours), which makes this drug intermediate-acting barbiturate.

Fioricet & Drug Testing

Although people don’t abuse barbiturates as they did a few decades ago, officials, companies or health professionals may still test for Fioricet. For instance, EIA (immunoassay technique) and GC/MS (gas chromatography/mass spectrometry) can detect barbiturates.

How Long Does Fioricet Stay in Your Blood?

Tests can detect Fioricet in your blood. Tests can detect Butalbital intake for up to 72 hours.

How Long Does Fioricet Stay in Your Urine?

Urinalysis is among the most popular forms of drug testing. Although testing for the 3 ingredients of Fioricet is not universal, Fioricet detection in your urine is possible. The detection time is up to 7 days.

How Long Does Fioricet Stay in Your Saliva?

Fioricet can be detected in swab tests, although it’s not a common procedure. The detectable levels in oral fluid show positive for up to 2 days.

How Long Does Fioricet Stay in Your Hair?

As most labs don’t do hair tests for Butalbital, there’s no precise data. However, have in mind that hair tests have a long window of detection (up to 90 days).

To prevent any accidents, always use Fioricet as prescribed.



Comments 4

  • I’m on fioricet to help with shoulder and neck pain due to fibromyalgia being so bad! Recently was sent to pain clinic because I’m going to have back surgery! The pain clinic doctor put me on dulided 4mg once a day! My family doctor wants to take me off of the fioricet because of any interaction. Can that be a problem?

  • I take care of my mentally handicapped son and my husband who has dimentia…I have terrible stress headaches and can’t take aspirin. I take 6 fioricet a day. My liver enzymes are high.i have tried massage therapy, chiopractor but fioricet works best. I take nothing s
    else with acetaminophen in it. What can I do. I ve tried PT. Neck stretches etc. I am 73

    • Perhaps you could try Fiornal. It has aspirin instead of acetaminophen, which is really tough on the liver. Maybe ask your Dr about the change. Both Fioricet and Fiorinal work well!

  • Can you just stop taking this drug if you have been talkin it for years for headaches most everyday?

Leave a Reply

Your email address will not be published. Required fields are marked *

Leave a Reply

Your email address will not be published. Required fields are marked *