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How Long Does Amphetamine Stay In One’s System?

amphetamines drug testing

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Table of Contents

Time Amphetamines Stay In The Urine,Blood, Saliva, And Hair

Amphetamine’s half-life is under 11 hours (that is how long it takes for the body to eliminate half of the ingested amphetamine). Chronic use, however, can be detected up to one week after the last use.
Amphetamines are detectable in the system within the following time spans:

  • Urine—minimum: 2-5 hours after use; maximum: 2-5 days
  • Blood— up to 12 hours
  • Saliva— minimum: 5-10 minutes after use; maximum: up to five days
  • Hair—minimum: 5-10 days after use; maximum: up to 90 days

Factors That Influence How Long Amphetamines Stay In One’s System

Factors that affect timeframes of amphetamine elimination from the body are various, and include the following:

  • Type of amphetamines used: Amphetamines have many street names and exist in numerous forms – legal and illegal, some more potent than others.
  • Age and metabolism: The younger the person, the faster their metabolism rate and amphetamine elimination are.
  • Body fat percent: Fat accumulates toxins from the body and acts like a sponge on amphetamines.
  • Kidney and liver function: Proper kidney and liver function is crucial for toxin clearance from the body.
  • The frequency of use: More time is needed for the body of heavy users to process amphetamines than one time users.
  • A person’s body pH: National Center for Biotechnology Information indicated that the body’s pH levels influence the rate at which amphetamines are eliminated from the body. “Alkaline people” (pH: 7-14) metabolize amphetamines slower than “Acid people” (pH: 0-7)
  • Routes of ingestion: Smoking, injecting and snorting fastens amphetamine effects, but also makes the elimination process faster.

Amphetamines Metabolism

Amphetamines are members of a chemical family of phenethylamines, whose members may be stimulant or hallucinogenic substances. Since amphetamine has a weak base (lipid soluble), when the body’s pH within alkaline limits (0-7), more of it is absorbed via lipid-rich cell membranes of the gut epithelium after ingestion (“Adderall XR Prescribing Information” United States Food and Drug Administration. Shire US Inc. December 2013). Further on, amphetamine enters the bloodstream and binds to plasma proteins at a certain level (15-40% of amphetamines). Plasma concentrations of amphetamine occur in 3 hours after ingestion. Finally, this chemical substance is eliminated via kidneys, where urine pH determines its half-life (alkaline urine prolongs the period needed for amphetamines to leave the kidneys).

Duration Of Amphetamine Effect last

The effects vary from person to person, and the key factor is the amount taken and the ingredients used to make Amphetamine. If one takes one dose of amphetamine, he/she will experience its effects between 30 minutes to 4 hours after use, although residual effects last longer – 3 to 12 hours, even for a few days.

Amphetamine Testing Information

The presence of Amphetamines can be detected with the help of the following tests:

Urine test

A commonly used drug test, since kidneys filter toxins from the body. The testee is asked to urinate in a cup with their name on it. The urine is then tested on the spot.

Blood test

Amphetamine Screen (Blood) test measures the amount of amphetamine in the bloodstream. A health professional draws the blood and sends it to a lab for testing.

Hair test

A small sample of the subject’s hair from the scalp line can be used to detect the presence of amphetamine in the body.

Saliva test

The easiest amphetamine presence test to perform is by using a saliva swab.

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Medically Reviewed By Michael Espelin APRN
Isaak Stotts

About Author

Isaak Stotts, LP

Isaak Stotts is an in-house medical writer in AddictionResource. Isaak learned addiction psychology at Aspen University and got a Master's Degree in Arts in Psychology and Addiction Counseling. After graduation, he became a substance abuse counselor, providing individual, group, and family counseling for those who strive to achieve and maintain sobriety and recovery goals.


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  • Ismail
    Hi My friend smoke ice after 4years for 36 hours on and off. How long will it stays in this body system? How long will it be in urine to detct?
  • Judith Bradley
    My friend took half a didtex. He has a Dr. Appt 6/11 will it be out of his system?